Patients with advanced cancers who took a drug designed to relieve constipation caused by pain killers lived longer and had fewer reports of tumor
progression than cancer patients who did not receive the drug, according to results presented Oct. 27 at the 2015 meeting of the American Society of Anesthesiologists in San Diego.
Not exact matches
That's not just because of Opdivo's failure — last month, Keytruda was shown to be better
than standard chemotherapy in untreated advanced lung
cancer patients with high levels of the PD - L1 protein, both stopping
cancer progression and extending patients» lives.
The results significantly alter existing assumptions of
cancer progression, indicating much greater genetic diversity in AML
than previously assumed.
The study by the University of Southern California «exemplifies a real opportunity for the oncology community, one that embraces an integrated approach to understanding
cancer progression and developing therapies that exploit evolution rather
than ignore it,» said Anderson.
Ceritinib provides longer
progression - free survival
than chemotherapy in crizotinib - pre-treated patients with non-small-cell lung
cancer harbouring an ALK rearrangement, according to results of the phase III ASCEND - 5 study presented at the ESMO 2016 Congress in Copenhagen.
In a second group of experiments using human tissue from patients with pancreatic ductal adenocarcinoma, which accounts for more
than 90 percent of pancreatic
cancers, Zheng and his colleagues also tracked down a link between the abundance of Sema3D in those tissues and the
progression of metastatic pancreatic
cancer.
Based on an analysis of existing evidence, published in an opinion article in the Nature Reviews Clinical Oncology journal on January 20, Dr. Narod argues that to achieve a cure, rather
than simply delay
progression or reoccurrence of the disease, women should be first treated with aggressive surgery to remove all clinically - detectable
cancer cells, followed by targeted chemotherapy to the abdomen (intraperitoneal chemotherapy).
Tumors are home to diverse immune cell types, some of which remain much less explored
than T cells and could also control
cancer progression» says Mikael Pittet, PhD, director of the Cancer Immunology Program in the MGH Center for Systems Biology and senior author of the Science
cancer progression» says Mikael Pittet, PhD, director of the
Cancer Immunology Program in the MGH Center for Systems Biology and senior author of the Science
Cancer Immunology Program in the MGH Center for Systems Biology and senior author of the Science paper.
The findings emphasize the value of implementing palliative medicine soon after a
cancer diagnosis rather
than waiting until later in the disease's
progression.
Levels of a small non-coding RNA molecule called let - 7 appear to define different stages of
cancer better
than some of the «classical» markers for tumor
progression, researchers from the University of Chicago report in the June 25, 2007, early online edition of the Proceedings of the National Academy of Sciences.
The
progression of pain with Ewing sarcoma tends to be faster
than in most other bone
cancers.
From life table modelling, the estimated number of deaths prevented is larger
than would be expected from reduction of cardiorespiratory deaths after smoking cessation, so most of the mortality gain is likely to be due to reduced
cancer progression.
In a life table model, assuming that these observations arose from a causal relation, we estimated the benefits of cessation to be substantial; the benefits on all cause mortality seem likely to be mainly due to reduced
progression of
cancer rather
than prevention of cardiorespiratory disease, but no studies reported
cancer specific death rates to confirm this.
The fact that the risk elevation was apparent directly after
cancer diagnosis, and decreased in magnitude over time, supports the conclusion that the risk increase may be traced to the diagnosis itself rather
than the emotional or physical suffering related to
progression of the
cancer or to its treatment.
The active surveillance group had twice as much
progression of their prostate
cancer, including metastases to other tissues including bone and lymph nodes,
than men who were assigned to surgery or radiation.
A 2017 study found increased disease
progression among men with recently diagnosed prostate
cancer who consumed more
than three servings of high - fat milk per day (30).
Compared with men who rarely eat eggs, men eating even less
than one egg a day appear to have twice the risk of prostate
cancer progression.
Why would less
than once a day egg consumption double the risk of
cancer progression?
Though I retired from active practice nine years ago, six of my former patients with early prostate
cancer have been using progesterone cream (along with diet, some vitamin and mineral supplements, and saw palmetto) for more
than five years and report their
cancer has shown no
progression.
Compared to men who hardly ate any eggs, men who ate even less
than a single egg a day had a significant 2-fold increased risk of prostate
cancer progression.
Vegan men tended to have significantly higher testosterone levels
than both vegetarians and meateaters (see graph here), which can be a risk factor for prostate
cancer, the reason plant - based diets appear to reverse the progression of prostate cancer may be due to how low their IGF - 1 drops (see Cancer Reversal Through D
cancer, the reason plant - based diets appear to reverse the
progression of prostate
cancer may be due to how low their IGF - 1 drops (see Cancer Reversal Through D
cancer may be due to how low their IGF - 1 drops (see
Cancer Reversal Through D
Cancer Reversal Through Diet?).
Less
than a single serving a day of either broccoli or Brussels sprouts, cabbage, cauliflower, or kale may cut the risk of
cancer progression more
than half.
So, even though vegan men tend to have significantly higher testosterone levels
than both vegetarians and meat - eaters — which can be a risk factor for prostate
cancer, the reason plant - based diets appear to reverse the
progression of prostate
cancer may be due to how low their IGF - 1 levels drop.