Not exact matches
Friedreich's ataxiais an inherited disease that causes
progressive damage to the nervous system, resulting in symptoms ranging from gait disturbance to speech problems; it can also lead to heart disease and diabetes.The ataxia of Friedreich's ataxia results from the degeneration of nerve
tissue in the spinal cord, in particular sensory neurons essential (through connections with the cerebellum) for directing muscle movement of the arms and legs.
If not degraded and removed, glycosaminoglycans can accumulate in cells and
tissues, resulting in
progressive, permanent
damage affecting appearance, physical abilities, organ function and often mental development in young children.
As we age, rogue cells, both human and foreign, can proliferate throughout the body unchecked and this
damaged tissue can contribute to
progressive disease.
This creates an accumulation of inflammatory cells locally and the chronic inflammation destroys the myelin sheath, leading to
progressive nerve
tissue damage.
Aging in most animals is accompanied by the
progressive accumulation of oxidative (or free radical)
damage to body
tissue, including brain
tissue.