Sentences with phrase «proliferation of cancer cells»

In many cancers, CDKs are overactive or CDK - inhibiting proteins are not functional, which results in the unregulated proliferation of cancer cells.

In another method, called target - based screening, potential anticancer drugs are identified by looking for compounds that mimic specific mutations that halt proliferation of cancer cells.

Rather than stimulating cancer cells, the receptor acts as a signal to inhibit growth factors, suppressing proliferation of the cancer cells.

Targeted drugs bind and shut down the activity of key aberrant proteins that drive proliferation of cancer cells.

According to Vogelstein, this catalog, which its developers named the «kinome,» constitutes an ideal collection of targets for cancer researchers seeking to stop the uncontrolled proliferation of cancer cells.

Studies (like this one) have even demonstrated a reduced proliferation of cancer cells in subjects who practiced intermittent fasting, and another study showed that alternate day fasting led to better reception of chemotherapy in cancer patients and a higher cure rate.

Both involve an uncontrollable proliferation of cancer cells — which then displace healthy cells, causing anemia and infection.

P.S.. All joking aside, if Seyfried IS right, and the genesis and proliferation of cancer cells lie in their aberrant sugar metabolism, then your work and others on the nutrition side may have helped with the dreaded «C».

Like the rest of its cruciferous family, the Brussels sprout contains high levels of sulforaphane, a phytochemical with high antioxidant activity that has been shown to regulate genes that control proliferation of cancer cells.

Thus, the protein HER - 2 is produced in excess, causing an excessive proliferation of cancer cells.

Mutation of this receptor — which is already the target of several cancer drugs either approved or in development — causes a proliferation of cancer cells.

In fact, when the researchers inhibited the secreted factor related to the activity of inflammatory cells, they observed a decrease in the proliferation of cancer cells.

«Ultimately, the virus is suppressing the immune system for its own benefit, and promoting the formation and proliferation of cancer cells may be just a side effect of that,» says Sharon Kuss - Duerkop, PhD, research instructor working in the lab of CU Cancer Center investigator Dohun Pyeon, PhD.

For years, attempts have been made to understand the mechanism behind the proliferation of cancer cells: they need metabolites to grow and proliferate as much as a vehicle needs gasoline or electricity to move.

In cancer cells it is interesting approach to block this information cascade and thereby block the proliferation of cancer cells.

The study focused on a cell protein called MYCN, one of a family of proteins that are notorious not only for stimulating the growth and proliferation of cancer cells, but also for their ability to evade targeted drug therapies.

That would be a way to influence the expression of many genes involved in the proliferation of cancer cells.»

Their research provides direct evidence that copper can enhance the proliferation of cancer cells.

Researchers hope to search the pint - sized flies for clues to the genes that control cell division — genes that might play a role in the growth and proliferation of cancer cells.

LA JOLLA, CA — A team of scientists at the Salk Institute for Biological Studies has identified why disruption of a vital pathway in cell cycle control leads to the proliferation of cancer cells.

Long associated with enabling the proliferation of cancer cells, the ancient cellular survival response regulated by Heat - Shock Factor 1 (HSF1) can also turn neighboring cells in their environment into co-conspirators that support malignant progression and metastasis.

The identified RIPK2 inhibitors potently inhibited the proliferation of cancer cells by > 70 % and also inhibited NFκB activity.

The PML / RARA * protein causes the proliferation of cancer cells in patients affected by acute promyelocytic leukaemia.

According to a study, the proliferation of cancer cells of the esophagus can be significantly inhibited with zinc supplementation.

Then, in 2001, scientists discovered that the use of IGF - 1 resulted in a proliferation of cancer cells, especially throughout the breast and colon, and a 2012 study found that both too much or too little IGF - 1 could contribute to dying from cancer; implying that IGF - 1 actually helped patients with terminal cancer live longer.

Sunflower seeds are also a good source of selenium, which has been shown to induce DNA repair and synthesis in damaged cells, to inhibit the proliferation of cancer cells, and to induce their apoptosis, the self - destruction mechanism the body naturally produces to eliminate worn out or abnormal cells.

Not only does this flavonoid slow the proliferation of cancer cells, but it blocks carcinogens from forming in the body.

Cancer cells survive by increased protein synthesis, so inhibiting ribosomes can slow the growth and proliferation of cancer cells.

Selenium has been shown to induce DNA repair and synthesis in damaged cells and to inhibit the proliferation of cancer cells.

The selenium in barley not only inhibits the proliferation of cancer cells, but also prevents heart disease and decreases the symptoms of asthma and arthritis.

Selenium has been shown to induce DNA repair and synthesis in damaged cells, to inhibit the proliferation of cancer cells, and to induce their apoptosis, the self - destruct sequence the body uses to eliminate worn out or abnormal cells.