Sentences with phrase «prolyl hydroxylase»

Singh, R. P., Franke K., Kalucka J., Mamlouk S., Muschter A., Gembarska A., Grinenko T., Willam C., Naumann R., Anastassiadis K., Stewart A. F., Bornstein S., Chavakis T., Breier G., Waskow C., and Wielockx B. HIF - prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady - state and stress.

Loss of prolyl hydroxylase - 2 in myeloid cells and T - lymphocytes impairs tumor development.

Rashim Pal Singh (Wielockx, TUD)-- «The Role of HIF - Prolyl hydroxylase 2 (PHD2) and Erythropoietin in the Hematopoietic System» (2013)

Soulafa Mamlouk (Breier, TUD)-- «Modulation of Prolyl Hydroxylase Domain 2 (PHD2) in Tumor Inflammation» (2012)

HIF prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady - state and stress.

HIF - prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady - state and stress.

Differential expression of prolyl hydroxylase 1 in patients with ulcerative colitis versus patients with Crohn's disease / infectious colitis and healthy controls.

Loss of epithelial hypoxia - inducible factor prolyl hydroxylase 2 accelerates skin wound healing in mice.

Lack of oxygen is sensed directly by a prolyl hydroxylase known as EGL - 9 in worms and EGLN2 in mammals.

The paper, by S.S. Karuppagounder at Burke Medical Research Institute in White Plains, N.Y., and colleagues was titled, «Therapeutic targeting of oxygen - sensing prolyl hydroxylases abrogates ATF4 - dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models.»

The activity of HIF is therefore strictly regulated by a set of oxygen sensors known as the HIF - prolyl hydroxylases (PHDs).

Not exact matches

In a series of cell - based studies, they showed that it both blocked a family of iron - containing, oxygen - sensing enzymes called hypoxia - inducible factor prolyl - hydroxylases (HIF - PHD) and, critically, protected neurons by activating genes that protect them from oxidative stress.

Activation of hypoxia - inducible factors in hyperoxia through prolyl 4 - hydroxylase blockade in cells and explants of primate lung.