The clinical trial results, published online in the Journal of Allergy and Clinical Immunology: In Practice, suggest that Verapamil represents
a promising novel therapy for the treatment of CRS with nasal polyps.
Not exact matches
Thus, mitochondrial rescue agents may be a
promising novel strategy for disease - modifying
therapy in LRRK2 - related Parkinson's.»
Our studies have improved our understanding of the basic biology underlying MMA, created a
novel animal model for testing interventions and, now, led us to the
promise of a new
therapy.»
Although the findings are
promising, Fornai cautions that «it will take some time to establish whether the use of lithium should be considered as a
novel therapy for ALS.»
The findings hold
promise for the development of
novel targeted
therapies with fewer harmful side effects.
It's the first CAR - T
therapy to come before the FDA, leading a pack of
novel treatments that
promise to change the standard of care for certain aggressive blood cancers.
«We are currently identifying the genes responsible for generating the DNA tether, which could be
promising novel targets for the next generation of cancer
therapies.»
However, despite its marked
promise for disease modeling, development of
novel therapies, and regenerative medicine, stem cell derived organoid technology faces many remaining challenges.
«Therefore, any potential
promising results get diluted because
novel therapies are not administered to those select patients who are most likely to respond, based on their tumors» molecular profile.
To build upon the encouraging early discoveries, Helmsley renewed and expanded its Crohn's funding for the Institute in 2013 to begin new work with three major aims: 1) continue studies of individual genes to determine how genetic differences between Crohn's patients and healthy individuals contribute to the disease; 2) evaluate
promising small molecules in disease - relevant studies and prioritize insights from genetics to help develop
novel therapeutics; and 3) begin basic experimentation in animal models with Crohn's disease to provide the data necessary to begin testing new
therapies in humans.
The Company's transformative gene repair technology presents a
promising opportunity to create
novel therapies that address the significant unmet need in the treatment of serious genetic neuromuscular diseases.
Both of these
novel therapies have, however, shown varying clinical results with disappointing cancer recurrences after initially
promising responses (13, 46).