Epigenetic dysregulation has been implicated in neurodegenerative disorders, while targeting histone acetylation is
a promising therapeutic avenue for PD.
In contrast, re-introduction of neurogenesis or stimulation of neuroplasticity in the adult brain both represent
promising therapeutic avenues to improve psychiatric and neurodegenerative conditions.
Not exact matches
Two drugs recently showed
promise in clinical trials, and now a study in Science Translational Medicine offers both an unprecedentedly deep explanation of how the disease progresses and introduces another potential
therapeutic avenue.
The ecRNAs, they say, are fundamental regulators of DNA methylation patterns in the adult brain through interaction with DNA methyltransferase enzymes, and the ecRNAs may offer a
promising future
therapeutic avenue to treat neuropsychiatric disease states associated with changes in DNA methylation, as they report in the July 7 issue of Nature Communications.
As a consequence, modulating nucleocytoplasmic transport could become a
promising and new
therapeutic avenue.»