Sentences with phrase «promote tumor formation»

These findings raise the possibility that Myc - Gcn5 could also work together to promote tumor formation.

Cancer researchers at Columbia have discovered three genes that undermine the DNA repair process and promote tumor formation in cells with BRCA mutations.

«Why premature cell division promotes cancers: Researchers have discovered how genes responsible for cell division, when mutated, disrupt the replication process of the genome and promote tumor formation.»

Repeated triclosan exposure and continued liver fibrosis eventually promote tumor formation.

We have found that the initiation of pancreatic cancer does not follow the classic paradigm seen in colon cancer where loss of a tumor suppressor gene initiates tumorigenesis and then acquisition of an oncogene promotes tumor formation.

By putting E. coli bacteria into mice that were raised under sterile conditions, the team also found that the presence of E. coli promoted tumor formation.

Not exact matches

But when their functioning is altered, as the UCL researchers observed in tumor cells, the mitochondria can promote cell migration, thus leading to the formation of metastasis.

Due to the lack of oxygen in the cancer cells, VEGF - A (Vascular Endothelial Growth Factor) is formed and this promotes the formation of new blood vessels to supply the tumor.

However, when these myeloid cells migrate to tumor sites, they can differentiate to tumor associated macrophages (TAMs), which can in turn stimulate the formation of blood vessels in tumors and promote enhanced tumor cell invasion and motility.

«These strategies would focus on promoting myelination in the peripheral nervous system for neuropathic disease or inhibiting Schwann cell over-proliferation that occurs during formation of peripheral nerve sheath tumors like neurofibromas.»

«Metastatic tumor cells can promote either bone formation or bone resorption,» lead author Kyoko Hashimoto explains.

We also found that the EphB4 receptor expressed on the surface of breast cancer cells can promote tumor xenograft growth by enhancing blood vessel formation through interactions with its preferred ligand, ephrin - B2, present in tumor endothelial cells.