During puberty, increased accumulation of gluteo - femoral fat
promoted by estrogen results in a «gynoid shape» of premenopausal women (Figures 3 and 4).
Not exact matches
Women with the KRAS - variant are also more susceptible to triple - negative breast cancer, tumors whose growth is not fueled
by the hormones
estrogen and progesterone, or
by the presence of a particular genetic mutation known as HER2, which
promotes cancer cell growth.
Overweight / obese males showed accelerated aromatization of androgens to
estrogens, inhibiting gonadotropin secretion
by activation of
estrogen receptors (ERs) of the hypothalamus that
promote hypogonadism (78).
Moreover,
estrogen can exert direct effects on fat tissue
by enhancing proliferation of preadipocytes, especially in females (232), and
by up - regulating sc α2A - adrenergic receptors
promoting SAT accumulation, notably in premenopausal women (233).
Too much
estrogen in the body (which can be caused
by all sorts of reasons including hormonal imbalances, over exposure to phytoestrogens like those found in soy, and xenoestrogens found in plastics) can cause inflammation, infertility and
promote accelerated aging.
The cancer
promoting effects of
estrogen on breast tissue are restricted
by lignan compounds which bind to
estrogen receptors.
Testosterone and
estrogen maintain bone density
by promoting bone building and slowing bone removal.
The second way fiber helps is
by promoting healthy
estrogen metabolism which aids in the reduction of elevated levels of androgens.
DIM helps to eliminate active
estrogen from the male body
by promoting its conversion into the «good» metabolites.
By promoting a healthy
estrogen metabolism, DIM adjusts the balance of estradiol to its «good» metabolites.
When activated
by progesterone, progesterone receptors bind to and «reprogram»
estrogen receptors, transforming them from agents that turn on cancer -
promoting genes to ones that turn on genes which slow down or even reverse the growth of cancer cells.
Diindolylmethane, or DIMÂ ® has been shown to help regulate and
promote a more efficient metabolism of
estrogen,
by supporting the body in metabolizing
estrogen into more of the protective 2 - hydroxyesterone rather than the proliferative 16 - hydroxyesterone.
Because
estrogen promotes the growth of some breast cancers, reducing the amount of this hormone in the body
by removing the ovaries may slow the growth of those breast cancers.
Spaying a cat before their first heat cycle lowers their risk of developing mammary adenocarcinoma
by lowering
estrogen levels that
promote cancer cell growth.