Sentences with phrase «promotes tumor cell proliferation»

It promotes tumor cell proliferation and resistance to apoptosis (programmed cell death after a certain number of cell divisions, a good thing when it comes to cancer cells).

«In our study, we demonstrated that alpha - KGDH, when coupled with Gcn5, induces histone succinylation and promotes tumor cell proliferation and tumor development.»

STC2 overexpression could promote tumor cell proliferation, invasion, and metastasis in prostate cancer, ovarian cancer, or neuroblastoma.

Not exact matches

But recent evidence suggests that Nanog promotes tumor growth by stimulating the proliferation of cancer stem cells.

They found higher levels of JAK1 in resistant tumors, which caused increased expression of epidermal growth factor receptor (EGFR)-- a receptor tyrosine kinase that promotes cell proliferation.

Using tumor cells from DLBCL patients, the scientists discovered that the inactivation of BTK in resistant tumors triggers the over-activation of alternative signals that promote tumor cell survival and proliferation.

In Wilms tumors, one set of mutations promotes abnormal and continued proliferation of the undifferentiated cells.

«Foxo1 is a tumor suppressor gene, but it promotes B cell proliferation in the germinal center,» he said.

In a recent study, senior author and Yale pathology professor Wang Min demonstrated that the tumors release substances called cytokines to attract macrophages, which then secrete growth factors that promote tumor cell growth and proliferation.

A great deal of evidence has now been amassed that stromal cell senescence plays an important role in laying the groundwork for tumor metastasis, promoting cell proliferation with inflammatory cytokines, encouraging angiogenesis, and degrading the tumor - suppressive action of an intact extracellular matrix.

Cyclin D1 has been observed in many human tumors and is likely to promote cell proliferation and differentiation by shortening the G1 / S transition.

Dr. Gollnick's laboratory explores how tumor cells co-opt the host immune system to promote chronic inflammation that leads to increased vascularization, suppression of anti-tumor immunity and increased tumor cell proliferation and migration.