Sentences with phrase «promoting cell migration»

But when their functioning is altered, as the UCL researchers observed in tumor cells, the mitochondria can promote cell migration, thus leading to the formation of metastasis.

CD90 promotes cell migration, viability and sphere - forming ability of hepatocellular carcinoma cells.

N - cadherin - mediated cell — cell adhesion promotes cell migration in a three - dimensional matrix.

Not exact matches

The researchers also report that saliva increased DENV infection of immune cells in the skin and enhanced immune cell migration to neighboring lymph nodes, which could promote the spread of disease throughout the body.

This study, published in the journal Microarrays, shows that lack of SOST in the bone microenvironment promotes the expression of many genes associated with cell migration and / or invasion, including long non-coding RNA MALAT1 in prostate cancer, suggesting that SOST has an inhibitory effect on prostate cancer invasion.

A group of researchers led by Kosuke Fujita, Visiting Researcher and Akito Maeda, Specially Appointed Professor at the HP Skin Regeneration, PIAS Collaborative Research, Osaka University clarified that cinnamtannin B - 1, or vegetable - based polyphenol, promotes the migration of Mesenchymal Stem Cells (MSCs) in blood circulation and accumulates them in damaged tissues (Fig. 1) to improve wound healing.

Fu plans to further explore the link between PLK1 and MAPK signaling in prostate cancer patients and determine whether PLK1 - induced EMT contributes to other cancer - promoting processes that go beyond cell migration and metastasis.

Recently published in the journal eLife and featured in a poster session at this year's American Association for Cancer Research (AACR) annual meeting, preclinical experiments show for the first time that PLK1 promotes the migration of prostate cancer cells by setting in motion a process that induces what is known as the epithelial - to - mesenchymal transition (EMT).

Researchers found that histatin - 1 promotes angiogenesis, as well as cell adhesion and migration.

It both promotes angiogenesis within the tumor and increased the migration of endothelial cells, which form the inner lining of blood vessels.

Long form collapsin response mediator protein - 1 promotes the migration and invasion of osteosarcoma cells.

Forkhead box C1 is targeted by microRNA - 133b and promotes cell proliferation and migration in osteosarcoma.

GCSF and hypoxia inducible factor - 1α (HIF - 1α) have been shown to up - regulate SDF - 1α in the infarcted area in a rabbit ischemia model and promote the migration of CXCR4 expressing cells towards cardiac tissues [47 - 49].

Secreted phosphoprotein 1 (SPP1, osteopontin) binds to integrin alphavbeta6 on porcine trophectoderm cells and integrin alphavbeta3 on uterine luminal epithelial cells, and promotes trophectoderm cell adhesion and migration.

Like other chemokines, SDF - 1 binds to its receptors to promote directional migration of cells to specific locations (chemotaxis)[6 - 9].

The LG3 module of laminin - 5 harbors a binding site for integrin alpha3beta1 that promotes cell adhesion, spreading, and migration.

One model, the «specification model», postulates that Toddler's primary role is to promote the specification of endoderm, which when defective leads to abnormal migration of mesendodermal cells (Chng et al., 2013).

Dr. Gollnick's laboratory explores how tumor cells co-opt the host immune system to promote chronic inflammation that leads to increased vascularization, suppression of anti-tumor immunity and increased tumor cell proliferation and migration.

Fibroblast growth factors activate mitogen - activated protein kinase pathways to promote migration in ovine trophoblast cells