These stem cells are called induced pluripotent stem cells (iPSCs) IPSCs are adult cells that have been genetically reprogrammed to an embryonic stem cell — like state by being forced to express genes and factors important for maintaining the defining
properties of embryonic stem cells.
Transformation of somatic cells with a set of embryonic transcription factors produces cells with the pluripotent
properties of embryonic stem cells (ESCs).
The results have been organized in an interactive, open - access database with a number of novel features and search tools to promote studies into the biological
properties of embryonic stem cells.
The debate might eventually be a moot point, as researchers continue to make convincing headway with induced pluripotent cells, which seem to have all
the properties of embryonic stem cells but which are created from adult cells.
Not exact matches
Such a single - step conversion
of an adult
cell into an
embryonic stem cell entirely avoids the question
of whether an embryo has been created, since the
cell produced by ANT - OAR never exhibits any
of the
properties of a single -
cell embryo.
Further investigation, says Resar, showed that these unusual
properties arise from the ability
of HMGA1 to turn on several genes involved in the Wnt pathway, a network
of proteins necessary for
embryonic development and
stem cell activity.
This gene is also known to help human
embryonic stem cells stay flexible enough to become any type
of body
cell, a
property known as pluripotency.
April 2012 - New research: Illuminating
embryonic stem cells Collaboration between two EU funded projects «Heroic» and «EuroSyStem», has provided new insights into
embryonic stem cells The teams used next generation sequencing technology to examine two key
properties of the
cells that influence their identity and behaviour: gene expression and gene regulation.
Immunological
properties of human
embryonic stem cell - derived oligodendrocyte progenitor
cells.
Stem cells harvested from amniotic fluid and placental tissue are readily obtainable and have properties of both embryonic and adult stem ce
Stem cells harvested from amniotic fluid and placental tissue are readily obtainable and have
properties of both
embryonic and adult
stem ce
stem cells.
The creation
of iPSCs began by studying proteins not only uniquely expressed in
embryonic stem cells, but proteins known to be functionally important in creating the unique
properties of these
cells.
«This discovery will advance our understanding
of stem cell epigenetics and chromatin structures, provide potential mechanisms on maintaining the hallmark
properties of ES
cells, and help researchers with the rich source
of information to better understand some
of the unique features — such as self - renewal and pluripotency —
of human
embryonic stem cells,» said Ng Huck Hui, Ph.D., senior group leader at GIS and a member
of the Singapore team that conducted this research.
This
property of HOXB4 can be used to expand
embryonic and adult
stem cells in vitro and in vivo.