The disease is notoriously difficult to diagnose, leading to a large
proportion of both false positives — where patients undergo surgery they don't need — as well as false negatives — where appendicitis is mistaken for gas or cramps and left untreated.
The procedure by Benjamini & Yekutieli [19], which keeps at the expected
proportion of false positives and is therefore much less conservative, also reveals no significant correlation (adjusted values are reported in the third table columns of Figure 2).
Not exact matches
Since the majority
of all investigated hypotheses are
false, if
positive and negative evidence were written up and accepted for publication in equal
proportions, then the majority
of articles in scientific journals should report no findings.
In legal terms, the
false positive rate means the
proportion of cases in which, on the basis
of the evidence, a suspect is found guilty when in fact they are innocent.