This enzyme, which is found in testicular, adrenal, and
prostate tumor tissues, plays a central role in allowing the body to produce testosterone from cholesterol.
An additional set of 18 prostate cancer tissue samples was analyzed by qPCR and five lncRNAs were found to be significantly higher in
prostate tumor tissues compared with matched normal tissues.
Not exact matches
As
prostate cancer progresses,
tumor cells may infiltrate this periprostatic adipose
tissue: this is a key step in the progression of this cancer, as it signals locally advanced disease (where the cancer can progress to nearby organs).
The scientists demonstrated that chemokine CCL7 is diffused through the PPAT to the area around the
prostate and that it attracts
tumor cells that express the CCR3 receptor towards the periprostatic adipose
tissue, the gateway to the rest of the body.
«While these
tumors appear to be muscle cells under the microscope, and clinicians had thought that they arose from muscle progenitor cells, that didn't explain why the
tumors can occur in
tissues that don't have skeletal muscle, like bladder,
prostate and liver,» he continued.
«The ability to test our ideas in
tumor tissues removed from patients underscores the unique and multi-disciplinary nature of our
Prostate Cancer Program, one of only eight
Prostate Cancer Programs of Excellence in National Cancer Institute Designated Centers,» said Dr. Knudsen.
In these circumstances, cells from primary
tumors in breast, colon,
prostate, or other organs invade lung
tissue via the bloodstream.
Early growth response 1 and fatty acid synthase expression is altered in
tumor adjacent
prostate tissue and indicates field cancerization.
A new approach to analyzing
prostate gland
tissue may help address a major challenge in treating
prostate cancer - determining which
tumors are unlikely to progress and which could be life threatening and require treatment.
In a study involving 12 patients with bladder cancer, who also underwent
prostate surgery as part of their treatment, she identified the ICOS molecule as the first immunologic marker identified in both
tumor tissues and the systemic circulation that can be used as a biomarker for monitoring of anti-CTLA-4 treated patients as a possible marker of therapeutic activity.
Prostate cancer is a type of tumor that forms in the tissues of the p
Prostate cancer is a type of
tumor that forms in the
tissues of the
prostateprostate.
The analysis of 278 transposition - induced
prostate, breast and skin
tumors detected
tissue - specific and shared data sets of known and candidate genes involved in cancer.
ERβ expression has been revealed to be greatly decreased in malignant
prostate tissue, reaching nearly undetectable levels with
tumor progression in more than 75 % of cases.
Prostate cancers are grouped according to tumor size, any spreading outside the prostate (and how far), and how different tumor cells are from normal
Prostate cancers are grouped according to
tumor size, any spreading outside the
prostate (and how far), and how different tumor cells are from normal
prostate (and how far), and how different
tumor cells are from normal
tissue.