On the contrary, recent evidence indicates that XMRV is a contaminant originating from the recombination of two mouse endogenous retroviruses during passaging of
a prostate tumor xenograft (CWR22) in mice, generating laboratory - derived cell lines that are XMRV - infected.
Not exact matches
Finally, I have a category of «other cancers» with exomes published in 2011; these include pancreastic cysts and cell lines, gastric cancer
tumors, and
prostate cancer samples derived through mouse
xenograft models.
In a series of lab experiments with cell lines, human
xenograft tumors in mice and primary human
prostate cancer samples, the researchers demonstrated that miR - 34a inhibits
prostate cancer stem cells by suppressing CD44.
Flavopiridol inhibits several cellular kinases and has demonstrated cytostatic and cytotoxic activity in vitro and in vivo in numerous human
tumor cell lines and
xenograft models (including human breast,
prostate, and lung carcinoma) at clinically achievable concentrations.