Already, Graham said, VRC researchers have shown that passive immunization with VRC01, one of the broadest and most potent bNAbs identified in recent years, can
protect rhesus macaques from virus challenge, adding that VRC01 is now ready to be used in human trials.
Not exact matches
And research in
rhesus monkeys suggests similar benefits in primates: One study found that monkeys eating 30 percent less than their cage mates appeared to be
protected from age - related diseases and had lower mortality 15 to 20 years later.
An earlier preclinical study found that
rhesus monkeys that were vaccinated with ZPIV developed a strong immune response and were
protected against two strains of Zika virus.
A purified inactivated virus vaccine derived from a Puerto Rican strain was shown to induce ZIKV - specific neutralizing Abs and
protect from virus challenge in mice and NHP models (115), and DNA vaccines encoding the prM / E genes of ZIKV elicited strong binding and neutralizing Abs in
rhesus monkeys (116, 117).
CR can lower the prevalence of age - related loss of function and multiple diseases, including tumors, cardiovascular disease, neurodegeneration, and
protects against diabetes, cancer, cardiovascular disease, sarcopenia, and neurodegeneration of certain brain regions in
rhesus monkeys (31).