Not exact matches
Estrogen is thought to be
protective of heart health through its beneficial
effects on cholesterol and because it increases the flexibility of blood vessels and arteries, allowing them to accommodate blood flow.
Estrogens have been reported to exert
protective vascular
effects in animal and observational but randomized clinical trials did not report such
effects in older women, even suggesting the possibility of an increased CVD risk in this setting, especially with combined
estrogen plus progestin therapy.
In their study, the Geneva researchers were also able to dissect the fine cellular mechanisms involved: Of the three
estrogens receptors, only one is mainly involved in this
protective effect.
The findings in this new study support earlier evidence from studies in animals that showed
protective effects of
estrogen against the flu.
They've discovered a group of immune regulating genes that become more active in the presence of
estrogen, offering a clue to how the hormone's normally
protective effects could go awry.
Estrogen demonstrated
protective effects from β - cell apoptosis (201), stimulates β - cell secretion (202) and improves insulin sensitivity (203) with antidiabetic
effects primarily described to ERα (68, 204).
It is known from previous research that the ER - beta
estrogen receptor often has a
protective effect.
New research from Emory University School of Medicine and Harvard Medical School provides insight into how
estrogen changes gene activity in the brain to achieve its
protective effects.
Because
estrogen may be linked to bone density, a woman who isn't having a regular period may not be benefiting from the hormone's
protective effects on bone health, Dr. Adimoolam explains.
The bad: When you lose
estrogen, you lose its
protective effects on your heart and bones, so your risk of osteoporosis and heart disease rises.
Women over 55 are significantly more likely than men to develop hypertension, perhaps because theyve lost whatever
protective effects estrogen might have provided.
(13)(14) Pregnant women are known to have less migraine headaches than women not bearing children, (13) which is indiciative of the elevated levels of progesterone during pregnancy and progesterone's
protective effects against
estrogen.
Estriol has been found to have beneficial immune - modulating
effects in patients with multiple sclerosis, increasing
protective immune responses and decreasing the number and volume of lesions seen in cerebral MRIs.22 Estriol is the primary
estrogen produced during pregnancy, when it is made by placenta from 16α - OH DHEA sulfate (DHEA - S), an androgen made in the fetal liver and in the adrenal glands.23
Recent papers have even suggested that the cardioprotective
protective effects of
estrogen may be largely mediated by 2 - CH30 E2, which inhibits vascular smooth muscle cell growth in arteries.
This does not come as a big surprise, as the cholesterol lowering
protective effects of
estrogen are well known.
The isoflavone phytoestrogens preferentially stimulate
estrogen receptor β, with
protective effects against breast and prostate cancer.
Meanwhile, DHEA is a precursor to other important hormones like testosterone and estradiol (
estrogen), and decreased DHEA levels are associated with many symptoms of aging, due to its
protective effects against damage from sources like excess cortisol.
In menopause, our bones begin losing the
protective effects of
estrogen, and we start to lose bone faster than we can replace it.
The
protective effects of
estrogen on the cardiovascular system.
The theory here was that perhaps there was a
protective effect provided by
estrogen, like that is seen in women, living longer than men.
Aside from their key findings on risk factors, they also found grade 1 level evidence in favor of a
protective effect for the female hormone
estrogen, cholesterol lowering drugs (statins), drugs to lower high blood pressure, and anti-inflammatory drugs (NSAIDs).