Poliovirus - specific CD4 + Th1 clones with both cytotoxic and helper activity mediate
protective humoral immunity against a lethal poliovirus infection in transgenic mice expressing the human poliovirus receptor.
Not exact matches
The Vaccine & Immunotherapy Center brings together many outstanding researchers within the Institute to focus on new immune based approaches to induce
protective tumor immunity, to control the tumor microenvironment, and to use
humoral and cellular immunity to control or eliminate cancer.
Production of these antibodies against the BBB and other neural cell antigens from a cell - mediated and
humoral immune response may indicate a pathological alteration of the
protective brain barrier.
The development of CMI is the most crucial factor in determining the ultimate outcome of FIPV infection.4, 5,12 Cats that produce
humoral antibodies but fail to generate an effective CMI response develop effusive FIP.4, 5 Experimental evidence demonstrates that cats with non-effusive FIP often have preceding, transient effusive disease.4 Thus, noneffusive FIP is believed to result from a partially
protective CMI response that is unable to wall off and contain the virus.4