Sentences with phrase «protein called app»

One of the main ingredients in these plaques, a peptide called beta amyloid, is created when enzymes cut up a protein called APP.

This protein is part of the enzymatic engine that churns out amyloid beta — a key molecular culprit in Alzheimer's disease — by snipping it out of a larger precursor protein called APP.

Not exact matches

The newly identified mutation affects a gene called APP, which encodes a protein that gets broken down into pieces, including β amyloid.

One interesting hypothesis by the study authors looks at the role that thyroid hormone plays in regulating the expression of a gene called the amyloid precursor protein (APP), which has a role in Alzheimer's.

Based upon activity in multiple CNS toxicity assays, we identified an exceptionally potent, orally active, neurotrophic molecule called J147 that facilitates memory in normal rodents, and prevents the loss of synaptic proteins and cognitive decline when administered to three - month - old APP / swePS1ΔE9 mice for seven months [7].

Beta amyloid is a fragment of a protein snipped from another protein called amyloid precursor protein (APP).