They used the model to determine how a point mutation in a family of DNA packaging
proteins called histone H3 drives formation and the continued growth of DIPG and other high - grade gliomas that develop in and around the thalamus.
The study, published September 19 in Science, focused on one well studied epigenetic modification — the methylation of a DNA
packaging protein called histone H3.
The precise timing of those cellular activities is critical to normal heart development, with disruptions in the structure
of proteins called histones linked to later heart problems..»
The DNA wraps tightly
around proteins called histones, and genes are then tagged with methyl groups that prevent the proteinmaking machinery in the cell from reaching them.
Such organisms cram meters of genetic material into the tiny nuclei by wrapping strands of DNA around clusters
of proteins called histones (SN: 1/10/15, p. 32).
One such example, Thomas said, are modifications of
specialized proteins called histones, which are responsible for packaging DNA in the cell nucleus and influencing how genes are regulated.
Other molecular changes — chemical tags added to DNA or to
proteins called histones — may affect health without injuring DNA.
Tsai's team also probed the biochemical mechanism by which environmental enrichment worked its magic, tracing it to
proteins called histones, the spools that DNA winds around to create complexes called chromatin in the nuclei of cells.
WOUND UP Archaea microbes wrap their DNA (represented in yellow) around
proteins called histones (purple) akin to the way plants and animals do.
Borrelli said they observed a remarkable decrease in expression levels of some 2,000 genes in this area, coupled with a widespread increase in modifications of basic DNA
proteins called histones — particularly those associated with reduced gene activity.
DNA is wrapped around
proteins called histones, which serve to package the DNA inside the cell nucleus and play an important role in regulating gene expression.
We're going to focus on a tried and true method of finding enhancers by isolating genomic regions that are bound to modified
proteins called histones.
It is
a protein called histone H3.3.
In the chromatin, DNA is wound around
proteins called histones.