Dr. Tjian discovered the first
human proteins called transcription factors that bind to specific sections of DNA and play a critical role in regulating how genetic information is expressed into the thousands of biomolecules that keep cells, tissues, and organisms alive.
Genes become more or less active at the touch of
proteins called transcription factors, each of which can influence hundreds or thousands of other genes.
Only some of the plant's 30,000 genes are active in a given root cell at a given time, thanks to
proteins called transcription factors that turn genes on and off as needed.
In the early 2000s, they injected mouse skin cells with between four and seven pieces of
protein called transcription factors.
Determining what parts of the genome are read to make protein and which are silenced is orchestrated by
proteins called transcription factors.
An entire class of
proteins called transcription factors, which regulate the activity of certain genes by interacting with specific sequences of DNA, has largely been ignored by the pharmaceutical industry because it's difficult to design and screen drugs against them.
Using computational methods, they used this data to reconstruct networks of
proteins called transcription factors.
Professor Jim Giovannoni presented his work on the identification of
proteins called transcription factors that control how tomatoes ripen.
The regulatory system of these cells consists basically of
proteins called transcription factors that control the activity of many genes — which in turn comprise the molecular machinery that instructs cells to develop into their mature, functioning state.