Sentences with phrase «protein coding genes within»

In fact, during the long course of evolution, this gradual transfer of genetic information into the nucleus has already occurred with the majority of mitochondrial genome, leaving behind a mere 13 protein coding genes within the mitochondria.

Not exact matches

Not long after the HD gene was isolated, studies led by MacDonald, also a co-author of the current investigation, found that a variation in the number of CAG trinucleotide repeats within the HD gene, which codes for a protein called huntingtin, is the primary determinant of the age at which HD symptoms appear, with a greater number of CAG repeats associated with an earlier symptom onset.

The repeated mutation that causes Huntington's disease lies within a gene that codes for a protein called huntingtin.

The vast majority of our 20,000 or so genes exist in the DNA within each cell's nucleus, as distinct from the 13 protein - coding genes inside mtDNA.

Silent mutations occur when the change of a single DNA nucleotide within a protein - coding portion of a gene does not affect the sequence of amino acids that make up the gene's protein.

Matching DPI peaks to the 5 ′ end of known genes within 500 bp revealed that 91 % of human protein - coding genes had a TSS supported by robust CAGE peaks.

Working within Mitocheck, a European research consortium, Jan has helped exploit sequence knowledge to systematically interrogate all 21,000 protein - coding genes one after another, identifying which are involved in cell division.

OR and V1R genes typically have coding regions that span a single exon, but we identified 54 OR and 15 V1R genes where at least one of the reconstructed transcripts has an intron within the protein coding sequence (as annotated in Ensembl).

To explore the possibility of common genetic pathways within the respective pathophysiologies, nine ADHD candidate single nucleotide polymorphisms (SNPs) in seven genes were tested for association with PD in 5333 cases and 12,019 healthy controls: one variant, respectively, in the genes coding for synaptosomal - associated protein 25 k (SNAP25), the dopamine (DA) transporter (SLC6A3; DAT1), DA receptor D4 (DRD4), serotonin receptor 1B (HTR1B), tryptophan hydroxylase 2 (TPH2), the norepinephrine transporter SLC6A2 and three SNPs in cadherin 13 (CDH13).

Supported by the resource of more than 42 000 unique human protein fragments generated within the Human Protein Atlas, representing more than 18 000 human protein coding genes, we offer proteome wide screening for autoantibody reactivity, on the, as well as downstream solutions for investigation of autoimmunity in hundreds of patient samples in paprotein fragments generated within the Human Protein Atlas, representing more than 18 000 human protein coding genes, we offer proteome wide screening for autoantibody reactivity, on the, as well as downstream solutions for investigation of autoimmunity in hundreds of patient samples in paProtein Atlas, representing more than 18 000 human protein coding genes, we offer proteome wide screening for autoantibody reactivity, on the, as well as downstream solutions for investigation of autoimmunity in hundreds of patient samples in paprotein coding genes, we offer proteome wide screening for autoantibody reactivity, on the, as well as downstream solutions for investigation of autoimmunity in hundreds of patient samples in parallel.

Human genetic studies have identified novel DNA variations in the genome associated with AMD, but most of them are not located within gene protein - coding regions, making their study a challenge.