Sentences with phrase «protein coding portions»

The point being that nobody knows how different the intron or non-protein coding sequences are between humans and other primates because the research quoted is only on the exons, or protein coding portions of the genome.

Not exact matches

By directly manipulating a portion of the prion protein - coding gene, Whitehead Institute researchers have created mouse models of two neurodegenerative diseases that are fatal in humans.

The protein - coding portions of these mRNAs are called exons.

Using whole - exome sequencing to examine portions of DNA containing genetic code to produce proteins, Amin and colleagues found that several variants of NKPD1 were associated with higher depressive symptom scores.

A genetic analysis revealed the culprit to be a mutation in the gene SMARCAD1, specifically in a small portion that codes for a protein only synthesized in the skin.

The new mutations were initially identified by sequencing the exomes (protein - coding portions of the genome) of three children with achromatopsia who receive their care at NYPH.

To illuminate the origins of chordate and vertebrates, we generated a draft of the protein - coding portion of the genome of the most studied ascidian, Ciona intestinalis.

Rbfox1 proteins were known to play a key role in splicing together coding portions of genes called exons to form mRNA, which is subsequently translated to form proteins.

Using technologies like whole genome or whole exome (the protein - coding portion of the genome) sequencing requires specialized equipment and advanced data analysis and is still relatively expensive.

For the first time, doctors have begun rolling out large - scale sequencing of the protein - coding portion of people's genome.

To determine if the girl carried any mutations that could explain her illness, the researchers sequenced the portion of her DNA that codes for proteins.

These RNA molecules are copied from portions of the genome that do not «code» for proteins.

Dr. Chung and her colleagues discovered the new mutations by sequencing the exomes (the portion of the genome that codes information to make proteins) of families with PAH without identified mutations.

Silent mutations occur when the change of a single DNA nucleotide within a protein - coding portion of a gene does not affect the sequence of amino acids that make up the gene's protein.

By rewriting a tiny portion of the mouse genetic code, the team developed a genetic line of mice with cells that could, under the right circumstances, produce a powerful protein called caspase when they start secreting p16.

In the last five years, major advances in genomic technology, especially in sequencing whole genomes and whole exomes (the portion of the genome that codes for proteins), have given rare disease research an important boost.

Of the tens of thousand of protein - coding genes in the human genome, only a small portion have an experimentally defined function.