Not exact matches
A new report by researchers in the Perelman School of Medicine at the University of Pennsylvania found that loss - of - function mutations to
Filaggrin - 2 (FLG2), a gene that creates a
protein responsible for retaining moisture and protecting the skin from environmental irritants, were associated with atopic dermatitis in African American children.
Filaggrin, a key
protein in skin barrier function, is deficient in adults.
This unexpected finding suggests that the
filaggrin deficit may not be the driving force for barrier issues and that treatments targeting this
protein might not be as beneficial for children with eczema as for adults.
Infants were also screened for mutations in the
filaggrin (FLG) gene, which codes for a key skin barrier
protein.
He recently has focused on a specific skin - barrier
protein called
filaggrin, which is broken down into a molecule called urocanic acid — the most potent absorber of UVB light in the skin, according to Elias.
Filaggrin is a
protein that helps the skin develop properly to form the outermost protective layer of skin.