Sentences with phrase «protein kinesin»

Cerasela Dinu (Howard, MPG)-- «Leveraging the motor protein Kinesin to manipulate DNA molecules in synthetic environment» (2006)

The researchers found that the motor protein kinesin - 5 (green) helps prepare the spindle by organizing its filaments, or microtubules, (red) by pushing them or acting as a brake.

«Cell division: Physical forces involved in creating the mitotic spindle probed: The motor protein kinesin - 5 appears to help organize spindle's filaments by pushing or slowing them.»

Not exact matches

We demonstrated that β - arrestins mediate the activity - dependent interaction of Smo and the kinesin motor protein Kif3A.

When a kinesin protein reaches the end, it detaches from the filament taking the tubulin to which it is bound with it.

This particular active material, originally developed at Brandeis University, borrows elements of cellular machinery, with bundles of rod - like microtubules forming the filaments, kinesin motor proteins acting as the engines, and ATP as the fuel.

The worm - like structures are microtubules driven by kinesin motor proteins.

Members of the kinesin superfamily of motor proteins are essential for mitotic and meiotic spindle organization, chromosome segregation, organelle and vesicle transport, and many other processes that require microtubule - based transport.

Proteins called kinesins, for example, are natural nanomotors that support cellular functions such as mitosis (the chromosomal process that creates two nuclei from one parent nucleus) and meiosis (when the number of chromosomes per cell is reduced by one half).

His team found that, from its vantage point at the minus - end of an existing microtubule, Kinesin - 14 attaches to a second protein that is bound to the plus end of a growing microtubule.

The researchers described how a protein called kinesin - 5 acts like a kind of molecular motor to help organize the mitotic spindle.

The base simulation will allow researchers to test more kinesins that move cargo from the nucleus to the outer limits of the cell and, eventually, dyneins, larger and more complex proteins that move cargo toward the center.

«We believe that kinesin - 5 has the ability to coordinate the speed of microtubules and keep them from going too fast or too slow,» says Forth, likening the protein to a gear box in a car.

Originally identified as a protein essential for mitosis in fungi, kinesin - 5 was first purified about 20 years ago by Scholey's lab who found that it is unusual because it has motor units at both ends, allowing it to link two microtubules and walk them past each other.

Other motor proteins, called kinesins and myosins, are much smaller and have specific functions, but dynein can turn its hand to a lot of different of functions,» Professor Knight said.

RESULTS: Here we report the identification of a de novo nonsense truncating mutation in one patient with SCZ, in kinesin 17, a synaptic motor protein.

Functional analysis of human microtubule - based motor proteins, the kinesins and dyneins, in mitosis / cytokinesis using RNA interference.

Molecular Basis for Specific Regulation of Neuronal Kinesin - 3 Motors by Doublecortin Family Proteins.

Inhibition of the motor protein Eg5 / Kinesin -5 in amyloid β - mediated impairment of hippocampal long - term potentiation and dendritic spine loss.

Volker Bormuth (Howard, MPG)-- «Optimized optical tweezers to study the mechanics of kinesin - 8: stepping, slipping, protein friction» (2009)

Molecular Basis for Specific Regulation of Neuronal Kinesin - 3 Motors by Doublecortin Family Proteins % U http://www.sciencedirect.com/science/article/pii/S1097276512005503.

The maize divergent spindle - 1 (dv1) gene encodes a kinesin - 14A motor protein required for meiotic spindle pole organization.

Kinesin - 8 is a low - force motor protein with a weakly bound slip state.

Tea2p is a kinesin - like protein required to generate polarized growth in fission yeast.

ARRY - 520, a novel selective kinesin spindle protein (KSP) inhibitor showed promising clinical activity both alone and combined with low - dose dexamethasone in a phase II clinical trial in patients with relapsed and refractory multiple myeloma.

Protein friction limits diffusive and directed movements of kinesin motors on microtubules.

In addition to receptors, GRIP has also been shown to bind to KIF - 5, a kinesin motor protein that is crucial in the transport of AMPA receptors within the neuron (Setou et al 2002).

«George was one of the first biophysicists who married experiments and theory by developing computational models of a bewildering variety of molecular machines — kinesin motor, flagellar rotary motor, RNA polymerase and protein translocation motors, «one - shot» actin polymerization motor and «slime - gun» motor of bacterial gliding,» Magilner said.