Sentences with phrase «protein myosin»

The interaction occurs principally in the biosynthetic and secretory pathways (Sans et al 2001) and SAP97 provides a linkage between the AMPA receptor subunit and the microtubule - based transport mechanisms, via an interaction with the motor protein myosin VI (Wu et al 2002).

It is driven by the motion of the motor protein myosin along filamentary actin strands.

Muscles contract because the muscle protein myosin uses its flexible head to ratchet its long tail along the filament of another muscle protein actin, dragging the ends of muscle cells inward.

Sarcomeres perform the muscle's contraction with the help of the contractile proteins myosin and actin, which cause the sarcomere to shorten.

Not exact matches

These findings suggest that the therapeutic protein was able to interact normally with its binding partners among the USH1 molecular complex (the proteins cadherin 23, protocadherin 15, myosin VIIA and harmonin), as required for the mechanoelectrical transduction apparatus of the hair bundle to function correctly.

The French team and a British group that discovered the mouse gene both decided to see if the mutation — which hampers the production of a protein called myosin VIIA — might, as in the mice, explain inherited deafness without other sensory loss.

The team has identified that aggressively spreading cancer cells express a protein called Myosin - 10 which drives cancer cell motility.

«Sarcomeres are mainly made up of actin and myosin protein strands called filaments.

The junction moves from the front to the rear of the protozoan, probably powered by actin and myosin protein filaments, like those in human muscle, constricting the protozoan and pulling the host membrane over it.

Although the anesthetics became bound to all of the various proteins, the most extensive binding was observed in three proteins, including actin and myosin - the muscle force producing proteins.

This constriction results from actomyosin contractility, a co-ordinated movement of filaments made of a protein known as actin, and a motor protein known as myosin.

In the dance, Lade is myosin - V, buffeted by other proteins in the cell.

Other motor proteins, called kinesins and myosins, are much smaller and have specific functions, but dynein can turn its hand to a lot of different of functions,» Professor Knight said.

«In our paper, we identify a direct interaction between focal adhesion kinase and myosin that drives the production of secreted cancer - promoting proteins,» says Alexander Meves, M.D., a dermatologist at Mayo Clinic.

«Through further functional studies we found that myosin IIa is also required for activation of the main guardian of the genome — a tumor suppressor protein called p53.»

Plant genomes encode the myosin XI family of myosin proteins.

Tra2ß Protein Is Required for Tissue - specific Splicing of a Smooth Muscle Myosin Phosphatase Targeting Subunit Alternative Exon.

Rho GTPases and the Downstream Effectors Actin - related Protein 2/3 (Arp2 / 3) Complex and Myosin II Induce Membrane Fusion at Self - contacts.

«Future studies are focusing on the molecular mechanisms underlying the ageing - related changes in skeletal muscle and the specific effects of HRT on the structure and function of the dominant protein in skeletal muscle, called myosin, which generates force and movement.»

Recently, the combination of these two techniques has produced a new generation of experimental setups enabling the simultaneous manipulation of a biological substrate (for example an actin filament or a DNA molecule) and detection / localization of an interacting partner enzyme (for example myosin or a DNA - binding protein).

A ring composed of actin filaments and myosin motor proteins pinches the cell apart, producing two daughter cells with equal amounts of cellular components.

We applied our technique to the study of molecular motors, using myosin II from fast skeletal muscle, and to protein - DNA interaction, for the lactose repressor (LacI) interaction with DNA.

Its structure was reminiscent of myosin, a motor protein.

To accomplish this, we used homologous recombination to ablate nonmuscle myosin heavy chain (NMHC) II - B by inserting cDNA encoding green fluorescent protein (GFP)- NMHC II - A into the first coding exon of the Myh10 gene, thereby placing GFP - NMHC II - A under control of the endogenous II - B promoter.

The researchers found, however, that in mice these specialized training cells couldn't train on the alpha - myosin heavy chain protein because none of that protein was being produced in those cells.

Furthermore, the studies also indicated that alpha - myosin heavy chain was not present in human thymus and that the T cells that sought out the protein could be found in the blood of healthy people.

In our second study we found that heterozygous mutations in genes encoding β - myosin heavy chain (MYH7), α - cardiac actin (ACTC1), cardiac troponin T (TNNT2), cardiac myosin - binding protein C (MYBPC3), and alpha - tropomyosin (TPM1) account for 30 % of cases of isolated LVNC in adult patients (Probst et al., 2011).

Researchers in the lab of Myra Lipes, M.D., have shown in both mice and people that myocarditis can be triggered by a protein called alpha - myosin heavy chain, which is found only in heart muscle and in especially low quantities in human heart tissue.

For example, clusters containing genes that are upregulated during the course of ES cell differentiation (Table 3) include in order of time of expression: cluster 30 that represents genes which take part in the formation of the three embryonic germ layers during gastrulation, i.e., Goosecoid, Cerberus like 1 homolog, Wnt3, Mesp1, Mixl1, mEomes and Even - skipped 1; cluster 15 containing molecular regulators of early mesoderm development including Bmp2, Bmp5, Msx1, Msx2, Cripto, Tbx20, Hey2, Smad6, Vegfr2 (Kdr), Foxf1 and Hand1; cluster 20, which comprises regulatory and structural genes linked to hemopoiesis such as Gata1, Nfe2, Klf1, Tie1, hemoglobins (Hba - x, Hbb - b1) and Glycophorin A; cluster 12, which is rich in genes involved in cardiac development, e.g., Mef2c, Myl4, cardiac Troponin T2, Tropomodulin 1, myosin binding protein C, Bves, Angiopoietin 1 and Angiopoietin 2; and, cluster 4, which consists mostly of genes associated with neuronal development and differentiation, for example, Neurog1, Neurog2, Olig2, Nkx6.1, Neurod4, Pou3f2, Pou3f4, Cacna2d3, Cacng4, Kcnq2 and EphA5.

These insights provide details about how myosin motor proteins work, and this knowledge could advance the understanding of diseases related to movement on a molecular level.

They attached fluorescent probes to parts of the myosin motor and observed distance changes between the glowing probe sites to time the protein's force - generating movements.

Myosin IIA's activity is regulated by RhoA and Rho - associated protein kinase (ROCK) signaling.

Skeletal muscle has different types of muscle fibres with distinct variants of ATP - dependent motor proteins or Myosins.

This causes the two main protein molecules (Aktin und Myosin) inside the muscle fibres to move relative to each other resulting in shortening (contracting) and lengthening (relaxing) muscle movement.

A final note on the fate of amino acids - once absorbed, amino acids can be used directly by cells for the synthesis of new enzymes or new cell structures, for the building of structural proteins (such as actin and myosin in the muscles), for the synthesis of OTHER amino acids (via transamination), or used for energy.

When you are able to increase the number of contractile proteins called actin and myosin, it increases the ability of muscles to contract and perform physical work.

Myofibrils are composed of long proteins such as actin, myosin and titin and others that hold them together.

Proteins also play structural roles, as the contractile proteins actin and myosin found in cardiac, skeletal, and smooth muscle and as the fibrous proteins collagen, elastin, and Proteins also play structural roles, as the contractile proteins actin and myosin found in cardiac, skeletal, and smooth muscle and as the fibrous proteins collagen, elastin, and proteins actin and myosin found in cardiac, skeletal, and smooth muscle and as the fibrous proteins collagen, elastin, and proteins collagen, elastin, and keratin.

This panel screens for autoimmunity against heart tissue by checking for myocardial (a protein the heart releases in response to stress) or alpha - myosin (cardiac tissue) antibodies.