Sentences with phrase «protein occludin»

These increases were accompanied by disruption of tight junctions and a decrease in expression of the tight junction protein occludin.

Tight junctions, regulated by a molecule called zonulin, as well as by conformational changes in the proteins occludin and claudin, are dynamic intercellular structures that modulate the trafficking or passage of macromolecules from the intestinal lumen to the submucosa and into systemic circulation (Fasano, 2012).

Not exact matches

While each of those three proteins was also significantly altered in patients with bone breaks, as was occludin, the researchers found that only in the concussed patients did elevated occludin correlate with elevated galectin 3.

With that approach, informed by prior research in animals, the research team ultimately identified four proteins (copeptin, galectin 3, matrix metalloproteinase 9 and occludin) that changed dramatically in the bloodstream of patients shortly after they had a concussion.

The two proteins that control your gut - lining permeability — occludin and zonulin — also control your blood - brain barrier permeability, and when they are elevated, it can lead to both leaky gut and leaky brain.

These tight junctions consist of proteins including claudins, occludins, and E-cadherin, among others.