Sentences with phrase «protein plays a key role»

The fact that so many proteins interact with the 26 bait proteins indicates that these original proteins play key roles in a complex process that wasn't apparent on the level of the «suspect» genes.

«Scientists identify proteins crucial to loss of hearing: Proteins play key role in genes that help auditory hair cells grow.»

The team discovered that the TCL1 protein played a key role in increasing glycolysis by activating a different metabolic pathway that is important for the self - renewal of stem cells.

Bcl - 2 proteins play a key role in cell survival by protecting against a form of cell suicide known as apoptosis.

They found more variants in men with azoospermia than in the controls, hinting that the protein plays a key role in sperm development in humans.

This protein plays a key role in the formation of the nervous system.

«The new protein plays a key role in the formation of adherens junctions of epithelial cells, and Listeria uses it for its own infectious process.»

The rising food demand is not just a result of the global population growth [although the planet can expect (UN medium variant) an estimated 2.3 billion extra people in 2050 — as no one even mentions the possibility of policy on that front]-- but also of an increasingly decadent average food consumption pattern, in which (next to globalisation of food production) the rising consumption of animal protein plays a key role.

Not exact matches

Every bite of turkey is an excellent source of high quality protein, a nutrient that is key for overall good health; it plays an important role in building, maintaining and repairing your body every day.

Protein, which has been called the «next super nutrient», is expected to continue to play a key role in functional food and beverage new product development...

Two proteins, collagen and elastin, play key roles in stretch mark formation.

«Our results show, for the first time, that these two proteins — a receptor and its corresponding binding protein — play a key role in the progression of rheumatoid arthritis pathology,» said Shiva Shahrara, associate professor of rheumatology at UIC.

Using the same computer - based approach, the team has now been able to target the c - FLIP (cellular FLICE [FADD - like IL - 1β - converting enzyme]- inhibitory) protein, known to play a key role in cancer stem cell maintenance and survival, described in previously published work by the Institute.

Salk Institute researchers discovered that a protein mutated in the premature aging disorder, Werner syndrome, plays a key role in stabilizing heterochromatin, a tightly packaged form of DNA.

In the past decade or so, researchers have also come to appreciate the key roles played by chromatin proteins and RNA in regulating gene expression.

The research team found that a key downstream effect of depleting the protein was that particular cells failed to migrate to the heart, where they would usually have played key roles in developing heart structures.

The much maligned prion proteins that cause mad cow disease and its human counterpart, variant Creutzfeldt - Jakob disease (vCJD), also play a key role preventing the progress of Alzheimer's.

The egg's very structure, its scaffolding of proteins that guide the chromosomes during cell division, may also play a key role in turning on the necessary genes.

Working with human breast cancer cells and mouse models of breast cancer, scientists identified a new protein that plays a key role in reprogramming cancer cells to migrate and invade other organs.

They then purified messenger RNA — a molecule that plays a key role in the production of proteins — from the cells in the animals» upper intestines, injected the mRNA into immature eggs cells, and looked for changes in iron uptake.

The paper focuses on two key molecular players in the story of influenza infection: a human protein called TRIM25, which was recently discovered to play an important role in the human immune response to flu infection; and a protein called NS1 present in all strains of the influenza A virus and shown to bind TRIM25 to keep it from doing its job.

Comparing proteins produced by normal genes to those produced by mutant Bt resistant ones, the team discovered that enzymes play a key role in determining whether or not a worm succumbs to the toxin.

Cannabinoid receptors are part of a large class of receptors known as G protein - coupled receptors (GPCR), which account for about 40 percent of all prescription pharmaceuticals on the market, and play key roles in many physiological functions.

As the researchers at Münster University, the Münster branch of the Fraunhofer Institute for Molecular Biology and Applied Ecology IME, the Technische Universität München (TUM) and TRM Ltd. (York, UK) demonstrated, using the example of Russian dandelion, Taraxacum kok - saghyz, there is one special protein (a so - called rubber transferase activator) which plays a key role.

RIMB played a key role in Roche's setting up of a peptide group and a biopolymer / bioengineering group for large - scale isolation of proteins.

This protein, called «NFAT,» appears to play a key role in the body's inflammatory response to an infection, which when uncontrolled, can be as bad, if not worse, than the infection itself.

Previous studies have shown that eIF4E plays a key role in regulating protein synthesis in the brain.

A team of scientists has now identified proteins, which play a key role in the production of rubber in the plant.

The UPR therefore plays a key role in secretory cells but also protects other cells of the body from the stresses associated with an accumulation of unfolded or misfolded proteins.

Hancock's group showed that inhibiting the enzyme p300 can affect the functions of another protein, Foxp3, which plays a key role in controlling the biology of Tregs.

Further investigation revealed that the increased susceptibility was due to a reduction in production by the innate lymphoid cells of IL - 22, a protein that plays a key role in the intestinal immune response.

Scientists from the Crick Institute, London and the Hebrew University, Jerusalem, discover a protein that plays a key role in turning cancer tumor cells into cancer stem cells that are able to renew outbreaks of the disease

Rbfox1 proteins were known to play a key role in splicing together coding portions of genes called exons to form mRNA, which is subsequently translated to form proteins.

Dr. Espen Spangenburg, associate professor of kinesiology, and his laboratory team are the first to identify that the BRCA1 protein is expressed in the skeletal muscle of both mice and humans, and that it plays a key role in fat storage, insulin response and mitochondrial function in skeletal muscle cells.

PLUMP PARTICLES Fats lurking in house dust can activate a protein in human cells that researchers think plays a key role in obesity.

He points out that sugars have a key role to play in the body, and are often what binds proteins to cells.

It's helped Bertozzi capture the first images of glycoproteins, proteins coated with sugars that play a key role in diseases such as cancer.

«Proteins in the cell envelope play key roles in cell function and bacterial physiology,» Sikora said.

In addition to determining that protein aggregation is regulated and requires active translation, Stowers scientists revealed that the mitochondria, the cell's powerhouses, play a key role in the mobility of these protein aggregates.

The protein mTOR regulates cell growth and metabolism and thus plays a key role in the development of human disorders.

The proteasome plays a key role in the smooth running of a healthy cell, facilitating cell renewal and death — chopping up proteins tagged for destruction into short polypeptides which can then be converted to amino - acids and recycled for use in building new proteins.

«We know from previous studies that the fission yeast version of DDX3X is thought to play a role in translation of key regulatory proteins, possibly by helping untangle parts of the RNA molecule.»

The working group of Dr. Susana Minguet, a biochemist — working in cooperation with Prof. Dr. Michael Reth, the chairman of the Department of Molecular Immunology at the University of Freiburg, and Prof. Dr. Miguel Ángel del Pozo of the National Center for Cardiovascular Research Carlos III («Centro Nacional de Investigationes Cardiovasculares Carlos III» (CNIC)-RRB- in Madrid, has demonstrated that the membrane protein Caveolin - 1 plays a key role in immune responses that trigger this type of disease.

The Altieri lab showed that the protein Akt, which plays a key role in cell signaling and metabolism, accumulates in mitochondria during hypoxia.

A team of researchers led by Hongkang Xi and Menno van Lookeren Campagne, of the Department of Immunology at Genentech, Inc., in South San Francisco, Calif., discovered that a pro-inflammatory signaling protein, or cytokine, called IL - 33, plays a key role in recruiting phagocytes to damaged retina and inducing retinal degeneration.

Some scientists suspected that the nucleolus — a small body inside the nucleus that puts together the cell's protein - producing machinery — could play a key role in this remarkable change.

The FUS protein normally plays a key role in the healthy functioning of neurons, which transmit nerve signals in the brain and spinal cord.

Johns Hopkins University biologists have found that a protein that plays a key role in the lives of stem cells can bolster the growth of damaged muscle tissue, a step that could potentially contribute to treatments for muscle degeneration caused by old age and diseases such as muscular dystrophy.

A variant in a region of the genome that is not coding for a protein can have a relatively large effect on a gene regulating bone health,» says Dr. Douglas Kiel, whose NIH - funded team at Hebrew SeniorLife and Harvard Medical School played a key role in the effort.

Joslin scientists in the Tseng Laboratory of the Section on Integrative Physiology and Metabolism previously discovered that one type of bone morphogenetic protein, BMP - 7, plays a key role in the control of brown fat formation and its heat - producing activity, which regulates whole body metabolism.