Sentences with phrase «protein produced by the gene»

Such changes, or mutations, may alter the function or the structure of proteins produced by the genes.

Therefore, investigators are searching for drugs that can increase the amount of normal protein produced by this gene.

Dr. Iavarone and his colleagues suspected that glioblastomas might be addicted to proteins produced by gene fusions.

Our research combines diverse techniques ranging from genomics, computational biology, tumour imaging, in vitro and in vivo functional models to study biological and clinical phenotypes.The proteins produced by these genes may serve as targets for novel chemotherapy drugs and other cancer treatments, or imaging scans.

Killary and colleagues earlier identified a cluster of genes involved in cancer migration and then analyzed the proteins produced by those genes.

Instead of being distinguished by a small number of crucial genes, as some geneticists had supposed, the two species appear to have surprisingly significant and widespread differences in the proteins produced by their genes.

However, the precise nature of the protein produced by the gene remains something of a mystery.

In 2010 biologist Valerie Hu of the George Washington University Medical Center and her colleagues found that brains of people with autism have low levels of a protein produced by a gene called retinoic acid — related orphan receptor - alpha (RORA).

The protein produced by this gene protects the chromosome ends of the DNA from damage, and controls telomere maintenance by the telomerase enzyme.

The analysis suggested that a protein produced by a gene called Olig2, which is only expressed in the neural progenitors that create motor neurons, promotes motor neuron formation by interfering with the activity of several members of another gene family — the Hes genes.

Drugs like trastuzumab and lapatinib block the protein produced by the gene.

When researchers want to study a specific gene, they often make slight modifications so a special protein tag that produces fluorescent light can attach to the proteins produced by their gene of interest.

The protein produced by this gene is a key defense for the cell — acting on a wide array of other genes to protect against many types of stress, including DNA damage and oxygen deprivation.

In affected children, the protein produced by the gene SMN1 — for «survival of motor neuron - 1» — is defective or missing.

The team found lower levels of TRNP1 in areas that were destined to form folds, and higher levels in areas that would not have developed them, suggesting that the protein produced by the gene inhibits more complex brain development in humans as well as in mice.

Five percent of the cohort had this mutation, and further study found that they had in their blood about half the amount of apoC - III, the protein produced by the gene APOC3.

Intriguingly and at first unhelpfully, most of the proteins produced by these genes were new to science, which meant the scientists could not rely much on studies of other biological pathways as a guide.

Researchers have isolated the gene involved, SMN, as well as the protein produced by the gene.

The most frequent high penetrance melanoma gene found to be mutated in melanoma families is CDKN2A and the protein produced by the gene is called p16.