In order to get rid of these toxic aggregates, cells have developed an elaborate
protein quality control system, which the researchers now describe in the journal Cell.
Not exact matches
The UPR is one part of the
quality control system in the ER, where some
proteins are made.
But work by Conn and others revealed that, when the
proteins are misfolded, the cell's «
quality control system» misroutes them within the cell and they cease to function only because of that misrouting.
«Basically, I wanted to see what happens in the cell when we produce just a bit more of this
protein than the
quality -
control system can handle,» Outeiro says.
For elucidating the unfolded
protein response, a cellular
quality -
control system that detects disease - causing unfolded
proteins and directs cells to take corrective measures.
On top of
controlled amounts of high -
quality protein, it's also fortified with vitamins and omega - 3's to help keep your pet's
systems running smoothly.