Sentences with phrase «protein side chain»

A number of different domain types interact with histone tails to read, write or erase protein side chain modifications.

DNA sequence discrimination by CAP derives both from sequence - dependent distortion of the DNA helix and from direct hydrogen - bonding interactions between three protein side chains and the exposed edges of three base pairs in the major groove of the DNA.

Not exact matches

The amino acid backbones snap together like beads on a string, the side chains arranged in a particular order for each protein.

And like protein structures, the TZP side chains were arranged in specific positions around the exterior of the rods formed by the backbone - backbone interactions.

Grate needed three things to mimic proteins: raw components with a backbone that can support a large variety of side chains; the ability to put the side chains in a particular order; the stickiness, which chemists refer to as non-covalent bonds.

Both substrate analogs are contacted exclusively by conserved ribosomal RNA (rRNA) residues from domain V of 23S rRNA; there are no protein side - chain atoms closer than about 18 angstroms to the peptide bond being synthesized.

Using their innovative approach, Emsley's team found that the sequence of protein motions follows a specific hierarchy as temperature increases: first the protein's solvent molecules, then the protein's side - chains and water molecules, and finally the protein's backbone.

In a protein the cogs and springs are the molecules that make it up: amino acids form its backbone each with side - chains of different molecules branching out on all sides in three dimensions.

Depending on the properties of the peaks on the diagram, scientists can determine the degree of motion of each atom in the protein, e.g. its backbone, a side - chain etc..

In the new study, the researchers were able to determine that the water molecules directly touched the protein's «side chains,» the portions of the protein molecule that bind and unbind with each other to enable folding and function.

Images produced by the study clearly show the structure of the proteasome complex — with the protein backbone of each of its 28 subunits visible along with most of the side chains of the proteins.

To do so, they added back a small amount of the NOE and RDC data, but just in the parts of the analysis that deduce the shape of the general backbone of the protein rather then the position of all the individual atoms in each amino acid side chain.

They then relied on their ROSETTA software to sort out the position of the atoms in the protein's side chains.

In this case, the handholds are the amino acid side chains of a protein that will interact with other proteins or small molecules, and the body is the folding of the protein that incorporates all the amino acids into one structure.

The Meiler laboratory leads the further development of ROSETTALIGAND (Meiler, J.; Baker, D. «ROSETTALIGAND: Protein - small molecule docking with full side - chain flexibility»; Proteins 2006; 65; 538 - 548).

SUMO ligases conjugate the protein, via its C - terminal carboxylate, to the side - chain lysine of target proteins to generate an isopeptide linkage.

Amongst the 22 amino acids vital for our body to function and manufacture proteins, glycine is the smallest and simplest, with only a single hydrogen forming its side chain.

The side chain of the molecule connects to the protein backbone at two points.

So, the difference in plant and animal - based foods must be either due to a lower percentage of protein, which might reduce IGF - 1 production, or due to some accompanying factor in the food such as sterols in animal products vs. phytosterols in plants, which have a different chemical structure such as their extra ethyl group on their side - chain.