«Gene discovered to cause rare, severe neurological disease: Epileptic encephalopathy linked to
protein trafficking gene.»
Not exact matches
Other
genes activated by the guide RNA encode mitochondrial
proteins that help cells regulate their energy metabolism, and
trafficking proteins that are involved in packaging and transporting other
proteins.
The huntingtin
gene encodes a large scaffold
protein, with many interaction partners, which is thought to be involved in intracellular
trafficking.
The symposium features presentations by Philippa Marrack and John Kappler talking on the T cell repertoire; William Paul on interleukin 4 as a prototypic immunoregulatory cytokine; Timothy Springer on lymphocyte
trafficking; Pamela Bjorkman on structural studies of MHC and MHC - related
proteins, and Jack Strominger on peptide presentation by class I and II MHC
proteins; Thierry Boon on
genes coding for tumor rejection antigens, including the first tumor antigen, MAGE - 1; and Philip Greenberg on the modification of T cells for adoptive therapy by retroviral - mediated
gene insertion Since then, the symposia series has attracted leading immunologists in the cancer vaccine and antibody fields, providing them with a comprehensive view of the promises and challenges in the development of cancer immunotherapies.
To study the effects of LRO - related
gene mutations, Dr. Huizing is performing fluorescent
protein expression studies using patients» cells in order to examine defective intracellular
trafficking.
The
gene is also involved in
protein trafficking — the routing of
proteins to their proper destination within cells.
Identify
genes and
gene products involved in
trafficking of
proteins to the lysosome of Baker's yeast; study their conservation in humans and their connection to human diseases such as Alzheimer's and cancer.
In a general sense, FP timers can be used in any situation where one wants to understand the relationship between the age of a cell,
protein, or cellular structure and a particular biological event (
trafficking to a subcellular location, start of
gene expression, development of a cell structure, etc).