Sentences with phrase «protein trafficking processes»
The observation that loss - of - function mutations in DENND5A causes epileptic encephalopathy suggests that DENND5A protein controls membrane trafficking pathways critical for normal neuronal development and strengthens the argument that protein trafficking processes in cells are critical for normal neuronal development and function.
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Endocytosis is a fundamental membrane trafficking process by which cells uptake external factors such as proteins and pathogens.
Selective imaging by correlated optical and electron microscopy of protein molecules of known ages will clarify fundamental processes of protein trafficking in situ.
By addressing CaaX processing of Chs4 we try to increase our current understanding on maturation and trafficking of proteins involved in chitin biosynthesis, but also aim to shed light on the still enigmatic biological function of the post-prenylation steps of CaaX processing.
In 2014, Anna earned her Ph.D. in Cell & Molecular Biology at Drexel University where she focused on characterizing Sonic Hedgehog signaling pathway and its role in Amyloid Precursor Protein (APP) processing, Amyloid - beta clearance, and trafficking to primary cilia.
Our group has discovered two protein - protein interaction networks that sit at the heart of numerous endocytic and trafficking processes: the EH (Eps15 Homology) and monoUb networks (9 - 13).