Sentences with phrase «proteins anchoring them»

Poldip2 also appears in mitochondria, indirectly regulating the process of lipoylation — attachment of a fatty acid to proteins anchoring them in membranes.

Cells communicate through proteins anchored in their membranes.

The rockets work like this: A protein anchored to the bacterium's membrane triggers the rapid polymerization of the protein actin; this provides an explosive boost, so the bacterium can push through the membrane of white blood cells and burst out to infect another cell.

Miller said that other proteins anchored to the cell surface in a similar fashion are known to play roles in cell proliferation, suggesting a possible mechanism for how HYAL2 might be involved in tumor formation.

The basic unit of a TAD is thought to be loops of chromatin pulled through a protein anchor.

Tim has also used remote homology tools to identify a new family of lipid transfer proteins anchored at contact sites, and highlighted the power of these tools through specific examples and a «How - To» guide.

Not exact matches

The protein acts as an anchor to stabilize the blood sugar.»

«The nanoparticle uses a protein present in the eye to serve as an anchor, and the gene is delivered when bound.»

Aiolos decreases the production of cell adhesion proteins and disrupts critical cell adhesion processes, including processes that allow tissue cells to anchor to their physical environment, a necessary requirement for cells to survive and spread.

NIAID scientists and their partners held the stalks together by anchoring them to the protein ferritin, which can assemble itself into nanoparticles.

The gene's sequence suggests that its protein may anchor the channel to the cellular skeleton, a steady framework from which it can detect any jostling.

Yet centromeres all do the same thing: They keep newly formed chromosomes together at first, then help anchor protein strands that pull chromosomes apart as the cell splits in two.

Kemp and Payne realized that if they could anchor the reporter protein to microtubules — fibrous structures that crisscross cells like railroad tracks — they might obtain the location information they needed.

A series of biochemical experiments found that the mechanical force disrupted proteins called integrins that help anchor cells to the scaffold of protein that surrounds them.

EB results from mutations to any of several genes that encode proteins crucial for anchoring the outer layer of skin, the epidermis, to the tissue below.

In the Nature Biotechnology study, the researchers used it to anchor proteins, and they also showed that the technique works on tissue that has been previously labeled with either fluorescent antibodies or proteins such as green fluorescent protein (GFP).

What's more, the staple proteins serve as anchor points for additional proteins: A method referred to as genetic fusion can be used to attach any functional protein domain desired.

They anchor strands of protein that attach to replicated chromosomes and help pull the paired chromosomes apart, so that each new cell gets just one copy of each chromosome.

DNA structures can be fabricated with nanometer - precision, and most importantly, other molecules such as RNA, proteins, peptides and drugs can be anchored to them with the same resolution.

«These glycans essentially provided an «anchor» for antibodies in this lineage as the surrounding viral proteins changed,» Andrabi said.

Advances in electron microscopy and native mass spectrometry enabled the researchers to determine that a critical component of the signaling system, anchored protein kinase A, remains intact during activation.

His experiments showed that Ataxin - 7 anchors one of the complex's enzymatic modules, which is responsible for removing chemical tags called ubiquitin from DNA - packing proteins.

Some examples of these nanoscale protein materials are scaffolds to anchor cellular activities, molecular motors to drive physiological events, and capsules for delivering viruses into host cells.

In adults, however, mitochondria become less mobile as mature neurons produce a protein called syntaphilin that anchors the mitochondria in place.

Thanks to an incredibly strong matrix of adhesive proteins, known as byssal threads, that it extrudes through its two - hinged shell, the mussel is able to anchor itself to almost any surface — even Teflon.

The pathway does this by generating a lipid group that anchors a protein called Rab11b to cell membranes, allowing Rab11b to deliver Arf6 to its site of activation.

The mevalonate pathway (MVP) is a metabolic pathway that produces the building blocks for a wide range of biological molecules, from cholesterol to the long - chain lipid groups that anchor certain proteins to cell membranes.

The RING finding is a bit of a surprise since in biology anchor proteins like rapsyn typically don't have this enzymatic activity.

Now scientists have found that a protein believed to help anchor that city of receptors also helps ensure their formation and function and slow their degradation.

To make his movable hydrogel, Lee borrowed chemistry from proteins that mussels use to anchor themselves to wet rocks.

The other family is comprised of a family of scaffolding proteins that bind to the auxiliary subunits and thereby anchor the receptors at the synapse.

Current understanding of Bcl - xL's structure describes a protein with three regions — a core that interacts with proteins involved in cell death, a flexible region lacking defined structure (IDR) with an unknown function, and a membrane - anchoring region that attaches the protein to specific sites within the cell.

Schmidt, P.H., Dransfield, D.T., Claudio, J.T., Hawley, R.G., Trotter, K.W., Milgram, S.L. and GOLDENRING, J.R. AKAP350: A multiply spliced A-kinase anchoring protein associated with centrosomes.

Regulation of Postsynaptic Structure and Function by an A-Kinase Anchoring Protein — Membrane - Associated Guanylate Kinase Scaffolding Complex.

ER stress - induced clearance of misfolded GPI - anchored proteins via the secretory pathway.

Central to this process is a large protein complex that physically anchors various molecules involved in heterochromatin assembly to the chromatin fibers.

Arabidopsis synaptotagmin SYT1, a type I signal - anchor protein, requires tandem C2 domains for delivery to the plasma membrane.

Parasporin - 2 requires GPI - anchored proteins for the efficient cytocidal action to human hepatoma cells.

Scaffolding by A-kinase anchoring protein enhances functional coupling between adenylyl cyclase and TRPV1 channel.

Regulation of A-kinase anchoring protein 79/150 — cAMP - dependent protein kinase postsynaptic targeting by NMDA receptor activation of calcineurin and remodeling of dendritic actin.

Mapping the protein phosphatase - 2B anchoring site on AKAP79.

Paladino, Simona, et al. «Protein oligomerization modulates raft partitioning and apical sorting of GPI - anchored proteins.»

These include the glutamate (EAAT1 - 5), GABA (GAT1 - 4), glycine (GLYT1 - 2), dopamine (DAT) and dicarboxylate (SDCT2) transporters as well as the glutamate - cystine exchanger and their anchoring and regulatory proteins.

In addition, because the moxFPs are highly monomeric, they are an excellent choice for fusions with integral membrane proteins and membrane associated proteins (i.e. GPI - anchored proteins), which are more susceptible to the oligomerizing effects of many standard FPs.

HYAL2 codes for a protein that is anchored to the cell surface of lung cells.

While the centrioles are involved in the recruitment of the proteins that form the PCM this last one will hold the property of nucleating and anchoring microtubules (MTs).

Given the multiple PDZ domain structure and the ability to interact with a wide range of different proteins, an obvious primary function would appear to be as a scaffolding and targetting protein, taking receptors and other proteins to their final destinations within synapses and anchoring them there.

As IL - 8 proteins disperse from the infection site, they anchor themselves to GAGs to provide «signposts» that help neutrophils find their target.

Using recombinant proteins and a sensitive protein interaction assay, we establish the binding interdependencies of all the other known RH5 complex components and conclude that the RH5Nt - P113 interaction provides a releasable mechanism for anchoring RH5 to the merozoite surface.

LPL is a pivotal player in TG metabolism, as mutations in LPL or in its cofactors (ApoC - II, glycosylphosphatidylinositol - anchored high - density lipoprotein — binding protein 1, lipase maturation factor 1) account for the majority of monogenic hypertriglyceridemia cases (25).