Sentences with phrase «proteins designed by»

In an animal model, they demonstrated for the first time that two proteins designed by the researchers not only recover muscle force and increase body weight in the sick animals but also significantly prolong survival.

Not exact matches

Their menu has everything to create a fulfilling and satisfying gluten - free meal, including starters, made - to - order sushi, Protein / Rice / Veggie Bowls — designed either by you or as Signature Bowls with pre-determined combinations — plus soups and salads, noodle bowls, and even Joe's Tea Bar.

The rebrand, executed by New York - based design firm Brandfire, changed the product's name from Ips to Ips Perfect Chip / Pop, shifted the packaging design to incorporate background colors (again), and gave more emphasis its protein content.

The STELLAR LABS ® Heart Healthy Vegetarian Eating System is an easy to follow, nutrient rich, heart healthy weight loss eating system featuring 5 meal plans designed by a licensed nutritionist with a list of heart healthy vegetarian food choices including 1 convenient STELLAR LABS ® Real Food Grass - Fed Protein Bar a day and 1 convenient STELLAR LABS ® Whey Protein Shake a day.

New SUPRO ® XT55 Isolated Soy Protein is designed specifically to improve the profitability of ready - to - drink, high - protein beverages by helping beverage manufacturers more effectively manage proteinProtein is designed specifically to improve the profitability of ready - to - drink, high - protein beverages by helping beverage manufacturers more effectively manage proteinprotein beverages by helping beverage manufacturers more effectively manage proteinprotein costs.

Meanwhile, sales of their Sous Vide Egg Bites, designed to meet thedemand for protein and snacking, have increased by 60 - percent since launch lastyear.

The company is also showcasing its Aubygel semi-refined carrageenans, used in a chocolate milk prototype designed to cut input costs for manufacturers, by replacing the protein stability, texture and flavour release of cocoa particles.

This protein powder, from Mommi, is specifically designed for use by anyone trying to get pregnant, during pregnancy, and throughout breastfeeding.

This formula by Enfamil is specially designed with easy - to - digest proteins.

People working in biomanufacturing need to be prepared for inspections by the US Food and Drug Administration and the European Medical Evaluation Agency designed to ensure that mass - produced proteins are of the same quality as those used in clinical trials.

With this approach, Lu and his colleagues were able to manufacture the designed transmembrane proteins inside bacteria and mammalian cells by using as many as 215 amino acids.

Scientists designed the bacteria by adding 18 new genes to their genetic circuitry, including thousands of DNA bases that code for light sensor proteins that respond to red, green, or blue light.

The researchers targeted mTOR with an experimental drug based on a prototype first designed by Shokat, a chemist and an expert in designing molecules to target this type of protein, called a kinase.

Other experimental options include: — AVI - 7537, a drug designed to block viral protein from being made, has shown human tolerability in early studies and could have 100 courses available by early 2015.

More studies are needed, but Krug believes new therapeutics could be designed to block the NS1 protein produced by the flu virus, hobbling its ability to evade the human immune system.

Designed by researchers at Sangamo Biosciences, the drug uses a natural protein that turns on the patient's own gene for helping nerve growth.

Bioprocess engineer Rafael Garcia of ARS and biochemical engineer Zhiyou Wen of the Virginia Polytechnic Institute and State University in Blacksburg are designing a study to grow EPA - and DHA - producing microbes using low - cost by - products of other processes, such as glycerol from biodiesel production and rendered animal protein from slaughterhouses.

By customizing the RNA sequences, the researchers can design vaccines that produce nearly any protein they want.

Small shining molecules developed by scientists at Linköping University in Sweden can be designed to distinguish between plaque of different proteins in the brain.

In drug design, for example, the function of a protein is determined by sequence comparison and 3D modelling programs.

The researchers then developed a molecule referred to as RK - 33 that was designed to disrupt DDX3's function by locking on to a portion of the protein.

The scientists added in their report, «The precise control over interface geometry offered by our method enables the design of two - component protein nanomaterials with diverse nanoscale features, such as surfaces, pores, and internal volumes, with high accuracy.»

TSRI Research Associate Giordano de Guglielmo, who was the study's first author, spearheaded the experiment in rat models of alcohol dependence, which were designed to express a special protein to distinguish only the neurons activated by alcohol.

To detect this sort of enzyme, the researchers designed nanoparticles coated with small protein fragments called peptides that can be cleaved by particular proteases called MMPs.

The findings make evacetrapib the third failure in a class of drugs known as cholesteryl ester transfer protein (CETP) inhibitors, which are designed to disrupt the natural process by which HDL cholesterol is converted into LDL cholesterol in the body.

This week, another team of scientists led by Ben Feringa of the University of Groningen in the Netherlands presents a light - activated nanovalve design based on a larger, 3 - nanometer - wide Escherichia coli protein channel.

«By imaging how proteins interlock in ultra-fine detail, down to the tens of billionths of a metre, our study should make it much easier to design new, more potent cancer drugs.

Chemical biologists led by Dana - Farber's Nathanael Gray, PhD, designed and custom - made a compound called THZ1 that forms a particularly strong bond with CDK7, rendering the protein essentially nonfunctional.

Just as cells of the immune system use antibodies to recognize pathogens, researchers in this study designed antibodies to recognize a protein over-expressed by these cancer cells, namely the protein mesothelin.

Research carried out by the University of Sussex and the Polish Academy of Sciences has identified two key proteins that allow mycobacterium tuberculosis, the causative agent of tuberculosis (TB), to «lay low» within cells designed to destroy them.

The findings suggest that reductions in the number of cartilage - producing cells, and greater risk for osteoarthritis, may be driven not just by lower adenosine levels but also by lower levels of the protein on the surface of chondrocytes designed to receive and pass on adenosine's signal.

By deciphering the rules of protein structure, David Baker has learned how to one - up nature and design new medicines and materials.

Using a novel method — design - based stereology — which enabled researchers to estimate the volume of the liver and the total numbers and sizes of its cells in 3D, it was found that the liver of mice on a low protein diet had decreased by 65 %.

Hsp90 inhibitors are among several innovative new types of treatment designed to attack cancer indirectly, by destabilising multiple different proteins required for the growth and survival of cancer cells.

By designing synthetic proteins that can only interact with a pre-determined partner, and introducing them into cells, the team revealed a key interaction that regulates the ability of embryonic stem cells to change into other cell types.

An entire class of proteins called transcription factors, which regulate the activity of certain genes by interacting with specific sequences of DNA, has largely been ignored by the pharmaceutical industry because it's difficult to design and screen drugs against them.

UNC scientists led by John Sondek, PhD, created a new biochemical tool to block specific types of downstream G - protein signaling, opening new avenues of research and potential drug design and discovery.

The work should be significant for pharmaceutical companies that design drugs through painstaking processes and at great cost by eliminating some of the trial and error in identifying new sites on proteins that could be more easily manipulated to treat disease, said Rice biological physicist José Onuchic.

Inspired by the earlier work, Deborah Fuller from the University of Washington in Seattle, USA, who is interested in developing influenza drugs and vaccines, teamed up with David Baker, also at the University of Washington, who is an expert in computational protein design.

ISIS - SMNRx is designed to treat all types of childhood SMA by altering the splicing of a closely related gene (SMN2) that leads to the increased production of fully functional SMN protein.

Typically, evidence that disease activity is truly «on - target» with respect to the proposed mechanism can only be examined once appropriate, highly selective chemical tools have been designed, synthesized and iteratively modified by teams of Medicinal Chemists and biologists working with the studied protein.

In the new research, his team used «protein engineering» to attach 12 copies of a small protein to a cube - shaped molecular cage, which was designed by a former graduate student of Yeates».

CRISPR / Cas9 gesicles are generated by the co-expression of Cas9 protein, a customer - designed sgRNA, and other proteins that stimulate gesicles to be released from the producer cell membrane.

So, the researchers forced expression of a dominant - negative TGF - β receptor type 2 (DNRII) onto LMP - specific T cells (DNRII - LSTs) that were specially designed to seek out and destroy proteins derived from the Epstein - Barr virus expressed by the tumor cells.

Quantitative proteomics can also be applied to identify major candidates of proteins targets and mechanism of action by specifically designed experiments using multiple drug / compounds in addition to that / those of interest and probing drug / compound - specific proteome responses to a treatment.

His research focuses on the long - term goal of designing small molecule therapeutics for prion diseases — fatal neurodegenerative diseases caused by the spread of misfolded proteins across the brain.

«When we eventually learn how alcohol consumption by cancerous mice selectively induces the metabolism of fat, but not protein, it may one day be possible to design a safer and more effective way to treat obesity.»

«Fitzpatrick and colleagues have paved the way for development of new drugs designed to prevent tangle formation by deciphering the molecular structure of the «tau» protein filaments that make up the tangles at atomic resolution.

The specific drugs designed by WAVE have been tested in cells in a petri dish, where they successfully lowered the mutant protein whilst leaving the normal version relatively untouched.

The core will provide assistance with project design, testing of BioID - fusion proteins, establishment and testing of cells expressing BioID - fusion proteins, large scale BioID pull - downs, arranging for candidate identification by mass spectrometry and data analysis.