In more detail, we will study the function of the central HIF - pathway
proteins during regeneration, cancer, local inflammatory disorders and hematopoiesis in mice.
During his doctoral and post-doctoral work under the mentorship of Jeffrey Goldberg, MD, PhD, and Larry Benowitz, PhD, Dr. Trakhtenberg discovered (1) how Set - β and PP2A
proteins regulate axon growth; (2) the role of serotonin receptor 2C in neurite growth and processing of visual information; and (3) that inhibiting the transcription factor Klf9 acts synergistically with zinc chelation in stimulating axon
regeneration.