Sentences with phrase «proteins into brain cells»

People already have ways to put proteins into brain cells.

Not exact matches

The results could provide insights into the Zika virus» recent emergence as a global health emergency, and also point to inhibitors of the protein p53 as potential leads for drugs that could protect brain cells from cell death.

Brain cells translate that genomic gobbledygook into rogue proteins, which do bad things inside nerve cells and eventually trigger symptoms, such as involuntary movements.

When injected into mice engineered with a tau mutation that makes the protein clump abnormally in brain cells, triggering memory and motor problems, the antibodies reduced the clumping and improved the animals» behavior.

The researchers have now provided further evidence for this new theory by showing that the abnormal protein coded for this genetic disorder can be transmitted to normal animals by the injection of diseased cells into their brain.

Published in the February 27 issue of Cell, the study found that tumor cells that reach the brain — and successfully grow into new tumors — hug capillaries and express specific proteins that overcome the brain's natural defense against metastatic invasion.

Svendsen injected into their brains a protein known to enhance neural development, called glial cell line - derived neurotrophic factor (GDNF).

As Pardridge studied the protein more carefully, he realized that it transports essential insulin into the cell and then out the other side, from which point the hormone travels into the brain to help regulate eating behavior.

The first step in the process involves inserting into those brain cells a gene that makes a light - sensitive protein.

The cells that make up the walls of blood capillaries are joined together more tightly in the brain than elsewhere in the body, preventing proteins and cells getting into the brain.

«The blood - brain barrier is chemically tight because the cells contain transporter proteins which make sure that substances entering the cells are thrown straight back out into the bloodstream again.

They found that when fibrinogen (a blood - clotting protein) leaks into the central nervous system, it stops brain cells from producing myelin and, as a result, prevents repair.

One of the genes involved in feeding the big brain, called SLC2A1, builds a protein for transporting glucose from blood vessels into cells.

The retina sits at the back of the human eye, and contains protein cells that convert light into electrical signals that travel through the nervous system, triggering a response from the brain, ultimately building a picture of the scene being viewed.

Originally from algae, the gene makes a protein called channelrhodopsin - 2, which reacts to blue light by admitting ions into the brain cells, activating them in the process.

THE GREAT DIVIDE Young brain stem cells (one shown dividing, left) pack old proteins tagged with ubiquitin (red) into one daughter cell.

When they stripped the vesicles of protein and their genetic cargo and injected them back into mice, the blood cells no longer went to the site of brain injury.

Still, when the brain cells and spinal cord cells of these babies were examined at autopsy, there was clear evidence that nusinersen had tricked SMN2 into producing a great deal more of the full length, motor neuron - protecting protein: two to six times more copies of SMN's messenger RNA were found in spinal cord samples from nusinersen - treated babies than in autopsy samples from untreated infants.

Mouse embryonic stem cells injected into rat brains express the AHD2 protein marker (yellow) characteristic of cells lost in Parkinson's disease.

Methylmercury crosses the protective blood - brain barrier by binding with an essential amino acid that has dedicated carrier proteins for shunting it into brain cells.

In studies of neural development in mice, Stahl found that TRNP1 produces a protein that determines whether neural stem cells self - replicate, leading to a balloonlike expansion of cortical surface area, or whether they differentiate into a plethora of intermediate stem cell types and neurons, thickening the cortex and forming more complex brain structures.

In Alzheimer's, this protein — present in all healthy brains — can accumulate and clump, developing into cell - damaging plaque.

«This data allows classification of all human protein - coding genes into those coding for house - hold functions (present in all cells) and those that are tissue - specific genes with highly specialized expression in particular organs and tissues, such as kidney, liver, brain, heart, pancreas.

A cellular protein called PAK1 stimulates the growth of dendritic spines, or protrusions, that allow communication between neurons, and Roy had a hunch that this protein — when transported into brain cells — might help bring silent engrams back into direct awareness.

The protein tau is normally found in brain cells, but scientists don't know why it clumps into tangles in people with Alzheimer's disease.

«Importantly, this analysis helped us identify the protein fibrinogen as the key culprit in MS, by demonstrating how its entry into the brain through leaky blood vessels impacted the health of individual nerve cells.»

From there, the ASOs get taken up into brain cells where they continue to suppress their target protein for a month or so, after which time more needs to be injected.

An intricate new three - dimensional protein structure is providing a detailed look into how brain cells communicate rapidly.

Bone marrow stem cells are recruited by GCSF to go into the brain and take away the harmful beta - amyloid protein which starts Alzheimer's.

Brain cells pick up the labeled leucine over the course of hours and it's incorporated into new copies of amyloid - beta and other proteins they make.

It hides in tofu dogs under aliases such as textured vegetable protein, hydrolyzed vegetable protein, and lecithin — which is troubling, since the processing required to hydrolyze soy protein into vegetable protein produces excitotoxins such as glutamate (think MSG) and aspartate (a component of aspartame), which cause brain - cell death.