Sentences with phrase «proteins than the mouse»

GTC stuck with goats because they reproduce more rapidly than cows and can yield more protein than mice or rabbits.

Not exact matches

In addition, mouse acute oral toxicity testing of the CRTI and PMI proteins showed a lack of toxic effects at dosages thousands of times more than any realistically conceivable dietary exposure from consuming GR2E rice.

Both TRPV1 / WT and KO mice treated with capsaicin and TPA together exhibited higher COX - 2 protein levels than groups treated with TPA alone (Fig. 2A), and tumors from TRPV1 / KO mice expressed the highest level of COX - 2 as a result of treatment with capsaicin and TPA together (Fig. 2A).

They also had lower levels of PER2, a protein involved in circadian rhythms, than unmutated mice, providing a possible molecular explanation for the unusual sleep patterns in the family.

When the researchers injected myelin - deficient regions in the mice with a drug that prevents destruction of the AXIN2 protein, the mice grew myelin sheaths faster than untreated mice, repairing the damage.

When the mice were just four months old — well before they showed symptoms of the disease — their synaptic mitochondria had accumulated approximately five times more amyloid protein than nonsynaptic mitochondria had.

For instance, Evan's blue, a dye that stains the cellular protein albumin, penetrates the brain 10 times more efficiently in stressed mice than in unstressed mice.

This permanent change gave the mice a higher dose of MIS protein than is found normally in females.

These epigenetic tweaks were then passed onto male pups, which produced higher levels of blood sugar - generating proteins in their livers than mice sired by unstressed fathers.

When the researchers then administered acetylcholine to the mice through the nebulizer, they observed that mice with the G protein - coupled receptors reacted more vigorously than those with only smooth muscle reactions, and they also showed increased airway restriction compared to their counterparts without the receptor.

When the researchers gave digoxin to mice that had E. lenta in their guts, higher levels of the active drug appeared in mice on a high - protein diet (containing arginine) than in mice that went without protein.

That's because the boosted mice produced normal — rather than high — levels of the amyloid precursor proteins from which plaques are made.

To ensure the introduced protein didn't interact with other parts of the neuron, the team used the mouse version of the gene rather than the nematode's usual invertebrate version.

Other researchers had linked the ank mutation to mouse chromosome 15; in this week's Science, Kingsley's team reports that it's a single typo in a previously unknown gene, which they called ank, that led to a protein about 10 % shorter than the normal version.

Drawing on an odd experimental technique invented more than a century ago but rarely done now, researchers have found that a blood - borne protein makes old mouse hearts appear young and healthy again.

In a boost for a controversial theory of aging, mice engineered to make a human protein that sponges up cell - damaging molecules live 19 % longer than other mice.

Furthermore, more than 75 % of mice infected with virus bearing the normal protein developed severe corneal autoimmune disease, whereas fewer than 20 % of mice infected with mutant virus did, and their symptoms were barely detectable.

In mice engineered so their macrophage cells would mimic those of people, expressing the human SIRPα protein, nanoparticles tagged with the CD47 peptide passports stuck around in the circulation rather than being gobbled up.

Results showed that tumor cells containing the protein carried anywhere from 10 to 17 times fewer breast stem cells, and tumors grown from the injected cells were about three times smaller than those in mice who had received tumor cells with depleted levels of HOXA5.

The researchers noticed that in highly infected mice, NK cells produced IL - 10 about 3.5 days into the infection — days later than when they'd produce IFN - gamma, a protein that helps to mount, rather than defuse, the immune system response.

In two independent studies, people and mice eating diets low in protein were healthier and tended to live longer than those eating protein - rich diets.

Using methods for analyzing gene expression in mice, they identified several members of the «BMP» family of proteins from among more than 20,000 possible candidates.

To investigate, Akhtar deleted the gene for Rac1 in female mice; their first litter of pups survived, but they were smaller than normal — probably because the milk they received contained less fat and protein than normal.

Using mice deficient in Del - 1, they found that the protein promotes proliferation and differentiation of hematopoetic stem cells, sending more of these progenitor cells down a path toward becoming myeloid cells, such as macrophages and neutrophils, rather than lymphocytes, such as T cells and B cells.

The quest for better opioids got a much - needed jolt in 1999, when researchers at Duke University showed that mice lacking a protein called beta - arrestin 2 got more pain relief from morphine than normal mice did.

He notes, however, that other attempts to stimulate bone growth in mice by manipulating cell signaling proteins have produced denser than normal bones — and he's surprised that Helms's team didn't see the same.

Although muscle cells did not reduce in size or number in mice lacking a protective antioxidant protein, they were weaker than normal muscle cells, researchers from the Barshop Institute for Longevity and Aging Studies at The University of Texas Health Science Center San Antonio found.

To see what was happening in the brains of these ankyrin - G mutant mice, the researchers analyzed the cell components in inhibitory synapses connecting with pyramidal neurons, finding that two proteins known as GAT1 and GAD67 — responsible for making the neurochemical GABA that dials back nerve impulses — were at much lower levels in the synapses on pyramidal neurons in ankyrin - G mutant mice than in normal mice.

The team suspects the difference may be due to the expression of a gene that codes for a growth factor called bone morphogenetic protein 2 (Bmp2); expression was 30 % higher in the developing forelimbs of bats than it was in mice.

In this respect, it is known that the circulating levels of myostatin protein in humans are considerably lower than in mice [14], [21], raising the possibility that the balance of the relative roles played by myostatin and by these other regulators may have shifted further away from myostatin in humans compared to mice.

As seen through a microscope, the leg bone of a normal mouse (left) makes considerably less new bone than a mouse that produces high levels of a signaling protein, WNT7B, that stimulates new bone growth (shown in pink on the right).

Researchers describe how they mapped organization of proteins within the mitochondria of mouse hearts, cataloging more than 3,000 interactions, in a paper in Molecular & Cellular Proteomics.

The team found that, over time, young mice made clot - busting proteins more quickly than old mice.

Multiple mouse models of SMA have been produced, generally by knocking out the endogenous mouse SMN1 gene and replacing it with one or more copies of the human SMN2 gene that produces much less full - length SMN protein than the SMN1 gene.

Likewise, mouse microglia bioengineered to lack EP2 vastly outperformed unaltered microglia, in A-beta-challenged brains, at such critical tasks as secreting recruiting chemicals and factors beneficial to nerve cells and in producing inflammation - countering, rather than inflammation - spurring, proteins.

The expression of a tumor - suppressing protein called TGF beta is more pronounced in the mammary gland of mice that are resistant to cancer (right column) than in the mammary gland of mice that are susceptible to cancer (left column).

7/5/2007 Why Liver Cancer Is More Prevalent in Males than in Females Production of a protein that promotes inflammation appears to be linked to the higher incidence of liver cancer in men than in women, researchers at the University of California, San Diego (UCSD) School of Medicine have determined in mouse studies.

Mouse feeding tests show GM technology is a safer way of delivering protection of crops from insects with the Bt - protein insect than is the traditional delivery method.

Using a mouse model for this disease, which in humans involves the destruction of white matter in the brain, a research team led by Albee Messing, director of the UW — Madison Waisman Center, found that a protein behind the symptoms of the disease, called GFAP, is broken down more rapidly in the body than researchers previously found in cell culture studies.

In January 2016, no less than three studies published in the journal Science and contributed by collaborative teams led by researchers at Harvard University and the Massachusetts Institute of Technology (Tabebordbar M et al. 2016), the University of Texas Southwestern Medical Center (Long C et al. 2016) and Duke University (Nelson, CE et al. 2016) reported using CRISPR (clustered regularly interspaced short palindromic repeats) / Cas9 (CRISPR - associated protein 9) genome editing approaches to permanently correct the genetic mutation in the well - known Dmdmdx mouse model for DMD (C57BL / 10ScSn - Dmdmdx / J — 001801).

The scid mice have a defective protein kinase, DNA - activated, catalytic polypeptide (Prkdc) gene, the new name for DNA - PK, and produce 90 % less DNA protein kinase than do B6 mice.

Protein powder can have an effect on pregnancy — A study on mice found that a high protein diet led to smaller birth weight than a low protein / high carbohydrate dieProtein powder can have an effect on pregnancy — A study on mice found that a high protein diet led to smaller birth weight than a low protein / high carbohydrate dieprotein diet led to smaller birth weight than a low protein / high carbohydrate dieprotein / high carbohydrate diet (24).

The mice that ate a high - carbohydrate, low - protein diet lived about 50 per cent longer than those on the low - carb diet.»

Brown, D. L. Canavanine - induced Longevity in Mice May Require Diets with Greater than 15.7 % Protein.

So it would appear that when you look at data that analyzes people eating real food, rather than mice eating processed mouse chow, protein intake has no correlation with overall longevity.

In a study done by scientists at Canada's British Columbia Cancer Research Centre, it was found that mice fed on a high - protein, low - carbohydrate diet had slower tumour cell growth than those fed a typical Western diet high in carbohydrates.

Your molecular clock is ticking faster 22.11.2009 High vitamin D level lengthens life expectancy of elderly Dutch 21.11.2009 Constant fight against appetite reduces life expectancy 09.11.2009 Stress reduces life expectancy at molecular level 07.11.2009 Animal study: melatonin extends lifespan 25.10.2009 Fish fatty acids reduce age - related physical performance decline 24.10.2009 Old muscles weaker, but tire less quickly than young ones 23.10.2009 How creatine lengthens your lifespan 20.10.2009 Melatonin keeps brain cells young 03.10.2009 Long marriage adds years to your life 18.09.2009 Drink three cups of tea a day and add five years to your life 11.09.2009 Life extending bacteria found in gut of Chinese centenarians 08.08.2009 Your initials determine how old you get 30.07.2009 Lecithin anti-aging supplement keeps hearing sharp 18.06.2009 Live ten years longer with just one multivitamin pill per day 06.06.2009 Life - extending effect of virgin olive oil shown in fat rats 22.05.2009 Daily dose of Echinacea lengthens life expectancy 24.04.2009 The less you sit, the older you'll get 21.04.2009 Animal study: nori contains life prolonging substance 06.04.2009 Vegetarianism is healthy, but not because of lack of animal protein 27.03.2009 Meditation lengthens lifespan 20.02.2009 Live longer with healthy fats 30.12.2008 Vitamin D delays aging at genetic level 28.12.2008 Physical exercise delays molecular aging by ten years 25.12.2008 How a low - carb diet helps against aging 23.12.2008 Vitamin D extends your life expectancy 22.12.2008 Too much growth hormone reduces life expectancy 07.11.2008 S - Words extend lifespan of writers and psychologists 11.10.2008 Creatine extends lifespan of mice 08.10.2008 Slim - waisted rats live longer 23.09.2008 Gingko lengthens rats» lifespan 12.09.2008 Strong men live longer 31.08.2008 Male orgasm prolongs life 23.08.2008 Ginkgo prolongs life 17.08.2008 Ginkgo protects the elderly against the first signs of Alzheimer's 16.08.2008