Sentences with phrase «proved cytotoxic»

Not exact matches

Specifically, TheraT ® has proven to be safe in animals as well as capable of eliciting uniquely potent antigen - specific CD8 + cytotoxic T cell responses and strong tumor control in mice.

Our data suggests that targeting DGKζ could prove to be a more useful clinical approach to augment cytotoxic T cell activity against tumor than targeting Cbl - b, perhaps resulting from enhanced Ras / ERK signaling.

Low - dose chemotherapy, radiation, or targeted therapies given in combination with immune checkpoint blockade may prove to be an effective and efficient way to immunize the body against tumor cells,» says CRI Scientific Advisory Council associate director James P. Allison, Ph.D., who identified the first immune checkpoint blockade with his discovery in 1995 that the cytotoxic T lymphocyte antigen - 4 (CTLA - 4) receptor inhibited T cell responses.

Although no studies have directly confirmed its effect on breast cancer stem cells thus far, the outlook is positive that one day the connection may be made considering its cytotoxic effect on breast cancer cells, in general, has already proven to be so high.