In 2014, the organization received a $ 24 million contract from the Division of AIDS (DAIDS) at NIH's National Institute of Allergy and Infectious Diseases (NIAID) to
provide drug discovery and development services that could lead to potential new drugs for the treatment and prevention of HIV infection.
MD Anderson's Institute for Applied Cancer Science (IACS) in combination with Deerfield will
provide drug discovery and development expertise, together with translational research focused at advancing autophagy therapeutics into trials in melanoma, lung and pancreatic cancers.
It could
provide drug discovery scientists with a shortcut to finding new drugs for many different types of cancer.
Not exact matches
Companies that
provide drug development and other product development services, equipment, software and services for research, manufacturing
discovery and medical diagnostics.
Founded in 1998 by Leonard A. and Ronald S. Lauder, the ADDF
provides critical seed funding to leading scientists conducting breakthrough
drug discovery and clinical research.
Strange as it may appear, though, our Christian clerics, principally the apocalyptic or doomsday prophesiers, it also turns out, do not receive divinely inspired visions that attempt to
provide practical answers to
drug discoveries in fighting our progressively escalating disease burden, and for better or for worse pragmatic solutions that should otherwise help us reverse our mournful state of relative technological, scientific and industrial backwardness.
The
discovery answers important questions about how the virus spreads and
provides a potential roadmap for the development of antiviral
drugs to combat both that virus and the more common Epstein - Barr virus, which is present in more than 90 percent of the adult population and is believed to have a nearly identical structure.
Recently, though, the
drug discovery components of the business have begun to
provide some of the industry's more intellectually challenging and financially rewarding jobs.
Although the small company I worked for did not conduct animal testing on site, my work in
drug discovery and
providing analytical support to pharmacology directly linked me to the pharmacokinetic and toxicology screening tests.
The journal
provides cutting - edge research including results from animal models that are likely to apply to patients, studies in human tissue that
provide new information about therapies or disease, and innovative reports of
drug discovery and development.
«Pain paradox»
discovery provides route to new pain control
drugs.»
Lowe, a medical chemist by profession,
provides daily commentary on
drug discoveries, the pharmaceutical industry, and relevant research and news, especially in chemistry.
«The scientists stand accused of emailing and downloading proprietary data about [GlaxoSmithKline] products and sending it to contacts working for the Chinese startup Renopharma, which
provides contract research services for early
drug discovery, according to its website.»
A large number of these companies are clustered in Toronto, Montreal, Vancouver, Ottawa, and Saskatoon and
provide a significant number of
drug discovery jobs in those areas.
Working on the premise that scientific research is the foundation of any technology industry, Hancock and others at UBC are writing a business proposal for an integrative centre for
drug research, with an objective of developing intellectual property in
drug discovery,
providing training for
drug discovery researchers, and developing new technologies.
«Our model
provides a new platform for
drug discovery and the study of bone formation that did not exist before,» he said.
The
discovery involved ORNL's Spallation Neutron Source, which
provides the most intense pulsed neutron beams in the world for scientific research and industrial development, and ORNL's Titan supercomputer, the nation's most powerful for open science — a one - two punch for illuminating the physical properties of potential
drugs that inform new design principles for safer, improved delivery platforms.
The
discovery now
provides a potential new target for
drug developers to home in on.
For Poirier, the key message was that R&D groups have a mandate of innovation and
discovery, whereas the marketing division's mandate is to do what is necessary to sell the
drug and
provide profits for the company shareholders.
Deuterium - and tritium - labeled pharmaceutical compounds are pivotal diagnostic tools in
drug discovery research,
providing vital information about the biological fate of
drugs and
drug metabolites.
The scientists stand accused of emailing and downloading proprietary data about GSK products and sending it to contacts working for the Chinese startup Renopharma, which
provides contract research services for early
drug discovery, according to its website.
This
discovery provides proof - of - concept for the use of natural GroEL / ES to fold D - proteins for a variety of mirror - image
drug discovery and synthetic biology applications.
The
discovery provides an opportunity to pursue the development of novel
drug therapies to address obesity, type 2 diabetes and related metabolic diseases.
Research continues to apply this fundamental
discovery to the development of innovative
drugs that could inhibit the X protein» highlights Dr. Simon Fletcher, from Gilead Sciences, Inc., whose team
provided the in vivo verification of the
discoveries made by the University of Geneva microbiologists.
The kinome, made up of enzymes called kinases,
provides a tremendous opportunity for
drug discovery.
Systems biology
provides better methods of
drug discovery: research teams can measure changes in genetic activity, protein levels and cellular behavior of the immune system in response to a potential vaccine.
«Techniques like this one that enable controlled, remote C - H activation are just beginning to be adopted by industry, and should
provide a boost to
drug discovery and development efforts for many years to come,» Yu said.
So similar are the two that researchers at the University of Georgia's Regenerative Bioscience Center have developed the first U.S. pig model for stroke treatments, which will
provide essential preclinical data and speed the
drug discovery process.
Lead researcher, Associate Professor Julianne Djordjevic, said she is optimistic this
discovery will
provide a new avenue for the development of safer urgently needed antifungal
drugs.
Overall, the upcoming involvement of academia in the
drug discovery process will
provide graduate students and postdocs the opportunity to gain experience and skills which are important for pharmaceutical and biotech companies whilst still engaging in hypothesis - driven academic research.
It is expected that the new technique will be applied to gene therapy in the future in addition to
providing a powerful tool for breeding useful organisms and conducting disease and
drug -
discovery research.
«This study
provides us exciting new information about how this virus is released from infected cells and opens the door for novel antiviral
drug discovery research.
Institute Director Professor Mark von Itzstein said his Group's research findings published in the journal Nature Communications
provided a new direction towards the
discovery of anti-viral
drugs against hPIV.
More patients are needed to clarify the possible correlation between the location of the mutation and disease severity, but understanding this relationship could be of great value in identifying molecules directly involved in clinical phenotypes and in
providing new targets for
drug discovery,» says Dr. Tohyama.
The strategy of
drug discovery may correct defects associated with genetic diseases as it continued to I - Stem is based on the access that pluripotent stem cells
provide molecular mechanisms involved in these diseases.
His research program has
provided innovative, seminal
discoveries in the field of neuropharmacology, including characterization of the roles of endocannabinoids in the reinforcing effects of abused
drugs and, more importantly, the involvement of dysregulated endocannabinoid function in the neuroplastic events that contribute to the pathology of addiction.
This will help us understand how the entire protein works together to block cell death, and may
provide new sites to target in
drug discovery.»
Enhancing the early detection of new therapies that are likely to carry a safety liability in the context of the intended patient population would
provide a major advance in
drug discovery.
«
Drug discovery is inherently risky, but the role of academics and start - ups is to
provide game - changing
discoveries that are the result of prolonged investigations in basic science, and can ultimately have a significant impact on human and animal health.»
ResMed, now entering its 32nd year, is a week - long graduate - level course
providing an accelerated program for medicinal chemists, biologists and other industrial and academic scientists who wish to broaden their knowledge of
drug discovery and development.
When Cellartis was founded in 2001, it initially pursued stem cell - based therapeutics but soon switched business models, opting instead to focus on
providing specialized cell types for
drug discovery and toxicity testing.
It may
provide an exciting additional target for further gene and
drug discovery.
This will
provide a rich source of chemical starting points for CBCS scientists to translate novel biology into innovative
drug discovery project, which may one day result in new medicines for patients in need,» said Garry Pairaudeau, Head of External Sciences, Innovative Medicines and Early Development Biotech Unit at AstraZeneca.
LA JOLLA, CA — A new method for rapidly solving the three - dimensional structures of a special group of proteins, known as integral membrane proteins, may speed
drug discovery by
providing scientists with precise targets for new therapies, according to a paper published May 20 in Nature Methods.
This effort, which will enhance deCODE's proprietary gene and
drug target
discovery work and may
provide genetic markers for additional diagnostic development, will leverage Illumina's Sentrix ® HumanHap BeadChips; Infinium ™ assay and LIMS (laboratory information management system); as well as analysis and visualization tools from Illumina's BeadStudio software.
She reported the
discovery that for mice that happen to have higher levels of certain fatty acids, the
drug actually
provided a cure for the disease.
Consequently, the safest investment in the ESC field may be «something where you're an enabler of the technology» by
providing the raw tools and ingredients for ESC research, says Steve Brozak, an analyst with WBB Securities in San Diego, Calif. «The time frame [for ESCs] is now for
drug discovery, soon for personalized medicine, and decades for therapeutic use,» adds Bob Palay, chairman and CEO of Cellular Dynamics International (CDI), a biotech company working with ESCs in Madison, Wisc..
We believe that leveraging human intuition through creation of a scientific game for
drug discovery can not only
provide a new avenue to discover therapeutic
drugs for protein targets, but can also contribute to the development of new sophisticated algorithms to use in computer aided
drug design.
This model offers unique capabilities for preclinical assessment of thrombosis risk in a patient - specific manner, including efficacy testing of anti-thrombotic agents, elucidation of mechanism of action, and, potentially, biomarker identification, all
providing a much - needed platform for
drug discovery and development.
• Flowmetric — Founded by CEO, Ren Capocasale, Flowmetric is a contract research organization focused on
providing polychromatic flow cytometry and cell sorting services to bio-pharma and
drug discovery companies.