Sentences with phrase «provide mechanistic understanding»

«Future studies can provide mechanistic understanding by examining how specific compounds in coffee are involved in telomere maintenance.»

Confirmation of the biomarkers in other cancer types will facilitate further characterization and validation to provide mechanistic understanding of how and why these specific gene - targets become modulated to accentuate or inhibit tumor metastasis.

Not exact matches

Furthermore, interactions between the environment and the epigenome may provide mechanistic insight into many toxicological phenomena that are not well - understood, such as non-genotoxic carcinogenesis, age - based windows of susceptibility, developmental reprogramming by early life exposures, and trans - generational exposure effects.

«This work provides the first demonstration of this combination of omics tools to gain a more mechanistic understanding of life in permafrost and the changes that occur during natural thaw,» said Jansson.

This work provided greater mechanistic understanding of airway remodeling that occurs as a result of viral exacerbation in respiratory diseases and an improved model for predicting the response to therapeutic candidates.

We want to gain comprehensive mechanistic insight into the division of human mitotic cells, provide a biophysical basis to understand nuclear organisation, and establish methods for systems analysis of the first mitotic divisions of mammalian embryos.

Multiple types of spectroscopy and electron microscopy capabilities available at EMSL, the Environmental Molecular Sciences Laboratory, a DOE Office of Science user facility on the PNNL campus, allowed the scientists to understand the catalyst surface at the atomic level and provide mechanistic insight into how oxygen vacancies migrate to the surface of the cerium oxide, creating pathways for highly active carbon monoxide conversion.

The results provide a valuable resource for future studies aimed at a mechanistic understanding of the function of O - GlcNAc on specific proteins during T cell activation.

The current results provide a potential mechanistic understanding for the observed differences between Vitamin C in supplements vs food in prior studies.

A limitation of the insights from the energy balance is that they do not provide a closed mechanistic understanding of what controls the ITCZ position.