Sentences with phrase «provide novel therapies»
Finally, Pollard wants to close the loop by incorporating code - writing approaches, such as genome editing using CRISPR - based approaches and synthetic biology, which are needed to test and validate hypotheses and could also provide novel therapies.
https://gladstone.org/ Not exact matches
It also provides novel insight into human mesenchymal stem cell - heart cell interactions that can guide future experimental studies to understand the mechanisms underlying mesenchymal stem cell therapy for the heart.
Furthermore, these mice would provide an excellent model to test novel therapies aimed at preventing metastasis.
The discovery provides an opportunity to pursue the development of novel drug therapies to address obesity, type 2 diabetes and related metabolic diseases.
The study authors write that using the LSC17 score to single out high - risk patients predicted to have resistant disease «provides clinicians with a rapid and powerful tool to identify AML patients who are less likely to be cured by standard therapy and who could be enrolled in trials evaluating novel upfront or post-remission strategies.»
«Using a novel model we developed to facilitate discoveries about the growth and spread of lymph node metastases, we show that angiogenesis does not occur in lymph node metastases, providing a mechanism for resistance to angiogenic therapy in these situations.»
The technique «potentially provides ways to create model systems for studying the genetic basis of diabetes, or to discover novel therapies to enhance existing β cells,» Ferrer says.
New studies from the Abramson Cancer Center of the University of Pennsylvania are providing fresh clues on potentially effective combinations with CAR T therapy in brain cancer as well as a novel therapeutic target in head and neck cancer, and also providing greater understanding of the mechanisms of resistance in pancreatic cancer.
Their findings, to be published in the July issue of the journal Cancer Cell, could explain why some tumors don't respond to radiation or chemotherapy, and provide novel routes for the development of new anti-cancer therapies.
We provide access to the latest medicines and technology, as well as the most advanced clinical trials including novel personalized targeted therapies including precision medicine and immunotherapy - some that are only offered at NCI - designated Comprehensive Cancer Centers like ours.
«The region - specific cells we found could provide tremendous advantages in the laboratory to study development, evolution and disease, and may offer avenues for generating novel therapies,» says Salk Professor Juan Carlos Izpisua Belmonte, senior author of the paper and holder of Salk's Roger Guillemin Chair.
«We are entering an exciting period of discoveries in genetics that may provide new insights about novel disease pathways that can be explored for development of therapies.»
Founded in 2014, ImmunXperts provides immunogenicity and immune - oncology screening services, assessing all aspects of the immune responses in donors and patients, supporting its partners in the full development cycle of novel drugs, biotherapeutics and stem cell therapies.
This «humanized» mouse is susceptible to human liver infections and responds to human drug treatments, providing a new way to test novel therapies for debilitating human liver diseases and other diseases with liver involvement such as malaria.
To build upon the encouraging early discoveries, Helmsley renewed and expanded its Crohn's funding for the Institute in 2013 to begin new work with three major aims: 1) continue studies of individual genes to determine how genetic differences between Crohn's patients and healthy individuals contribute to the disease; 2) evaluate promising small molecules in disease - relevant studies and prioritize insights from genetics to help develop novel therapeutics; and 3) begin basic experimentation in animal models with Crohn's disease to provide the data necessary to begin testing new therapies in humans.
In addition, we are studying genetic background effects on onset and progression of ALS symptoms in the mouse model in hopes that these will provide novel targets for therapy.
A recent analysis of results from a randomized controlled clinical trial indicates that abaloparatide - SC, a novel therapy for osteoporosis, provides consistent protection against bone fractures in postmenopausal women with...
The new iPS cells generated using novel methods may represent biomedically - and clinically - ideal cells, providing potential platforms for studying human disease mechanisms and achieving the long - term goal of personalized cell - replacement therapy.
Additionally, this technology could provide a novel research model by which we transplant cells in vivo to study a disease and its progression from the onset, as well as directly test how effective new therapies are.»
The present studies provide multiple novel findings relevant to the development of astrocyte transplantation therapies for treatment of the injured or diseased central nervous system.
The goal of this Center of Excellence is to better define thrombus development in patients with cancer, test the efficacy of novel therapies, develop new preclinical models, and create and expand biorepositories to provide a valuable resource to researchers across Cleveland Clinic.
«These findings provide hope that long - term improvements in glucose control may alter the course of kidney disease in people with type 1 diabetes,» said JDRF program director Helen Nickerson, Ph.D. «This reinforces the importance of improved glycemic control as we pursue novel therapies to slow or reverse loss of kidney function.»
Cellular stress signals sent by macrophages amplify neuroinflammation, provide novel drug targets for MS therapy
This research provides direction for novel therapies to address complications and their prevention.
The derivation of induced pluripotent stem cells (iPSCs) provides new possibilities for basic research and novel cell - based therapies.
Veterinary clinical studies conducted to investigate novel therapies or to collect samples or information to gain further understanding of a disease provide the best scientific evidence to guide the clinical care of animals, and oftentimes, people too.
Lectures provided on Mast cell tumors, Updates in Canine Lymphoma, Novel Therapies, Oral tumors and Soft tissue sarcoma.
Dr. Hazzah's area of interest is Complementary and Alternative Medicine (CAM) and offers a novel approach to veterinary cancer therapy by combining conventional Western therapies with complementary Eastern therapies to provide a «whole patient» treatment approach.
KEY ACHIEVEMENTS • Saved a patient's life (who was showing signs of stroke) by providing immediate medical assistance in the absence of the head nurse • Devised a novel way of keeping patient specimens from becoming contaminated through implementing safe carriage channels • Introduced the concept of preventative maintenance on medical equipment which decreased breakdowns by 75 % • Rehabilitated a stroke victim who had 85 % paralysis on both sides, by providing dedicated physical therapy support over a period of 4 years