Sentences with phrase «provides mechanistic insights»

Furthermore, interactions between the environment and the epigenome may provide mechanistic insight into many toxicological phenomena that are not well - understood, such as non-genotoxic carcinogenesis, age - based windows of susceptibility, developmental reprogramming by early life exposures, and trans - generational exposure effects.

By providing mechanistic insights into how these bacteria interact with the host, this research will contribute to efforts to devise these future therapies.

Molecular dynamics and density functional theory calculations provide mechanistic insights into the reaction steps.

The Liver - Chip also provided mechanistic insight into drug action.

During her residency in Human Genetics at the University of Bonn she pursued her research interest both in immunology and human genetics by investigating expression quantitative trait loci (eQTLs), which underpin innate immune responses, and provide mechanistic insights to complement genome - wide association studies.

Our current studies therefore, are not only allowing us to investigate discrete interactions that lead to H. pylori - induced neoplasias but also are providing mechanistic insights into other malignancies that arise within the context of microbially initiated inflammatory states.

Multiple types of spectroscopy and electron microscopy capabilities available at EMSL, the Environmental Molecular Sciences Laboratory, a DOE Office of Science user facility on the PNNL campus, allowed the scientists to understand the catalyst surface at the atomic level and provide mechanistic insight into how oxygen vacancies migrate to the surface of the cerium oxide, creating pathways for highly active carbon monoxide conversion.

74/4: 15 Functional analyses of type 2 diabetes - associated loci provides mechanistic insight into genetic susceptibility.

Not exact matches

«Our structures of the complexes of the circadian clock proteins of cyanobacteria provided important mechanistic insights, but are static snapshots of a system that's continuously moving and changing hour by hour,» said LiWang.

This direct link between Exocyst and WRC complexes provides a novel mechanistic insight into the spatio - temporal regulation of cell migration.

«The data presented at AACR provide important new models and mechanistic insights that inform our planned development efforts to evaluate the ability of microbiome therapy to augment immune checkpoint inhibitors,» said David Cook, Ph.D., Chief Scientific Officer and Executive Vice President of Research at Seres.

Together, the expected results will provide fundamental mechanistic insights into the structure and function of the newly discovered interbacterial nanotubes.

Our experiment provides new mechanistic insights into the role of memory systems in informing this process.

We want to gain comprehensive mechanistic insight into the division of human mitotic cells, provide a biophysical basis to understand nuclear organisation, and establish methods for systems analysis of the first mitotic divisions of mammalian embryos.

As we demonstrate here, climate models provide new insights into the historical, current, and future populations of marine turtles and provide a mechanistic modeling framework for considering anthropogenic climate change.

This 3D proteomics brain data can be integrated with parallel 3D transcriptomic studies to possibly provide insights to interesting targets for either therapeutic intervention or further mechanistic studies.

Identifying a reliable signature pattern of altered RS activity for chronic pain could provide strong mechanistic insights and serve as a highly beneficial neuroimaging - based diagnostic tool.

A limitation of the insights from the energy balance is that they do not provide a closed mechanistic understanding of what controls the ITCZ position.