Not exact matches
The smart gel could
provide structural rigidity in organs such as the lungs, and can contain
small molecules like water or
drugs to be transported in the body and released.
«They also
provide a promising strategy for identifying
small molecule drugs designed to treat Alzheimer's disease and other neurological disorders.»
The cells generated in the Zeng lab may not only
provide a potential unlimited source for cell replacement therapy for Parkinson's disease, but also offer an unprecedented opportunity to develop screening models for assessing
small molecule drugs and to clarify the mechanisms of disease.
The facility maintains a
small molecule library of ~ 100,000
drug - like
small molecules for high - throughput screening and
provides access to liquid handling robotics and a multilabel plate reader.
«We have
provided evidence, in collaboration with Erich Wanker from Berlin, that such activation can be achieved, in principle, with an experimental
small molecule drug [called] geldanamycin.
A feature article in the same issue of Science
provides a perspective on this research «The Synthesis Machine: An automatic device that makes
small organic
molecules could revolutionize
drug discovery» (full text courtesy of Burke Lab).)
Because LINGO1 has be shown to have a negative impact on neuronal development and survival, inibiting it with a
small molecule drug may
provide an effective approach for developing a treatment for the severe forms of essential tremor.
Chemotype Evolution thus
provides an efficient and systematic approach for converting peptides into
small molecules, a goal that has remained a significant challenge in
drug discovery.