They also ruled out other possibilities, including the
gene spontaneously mutating back to the
normal form, the existence
of more than two
copies of the hothead
gene, or closely related DNA sequences
providing a template for repairs.
As reported in the new study, the researchers were able to postpone the onset
of hearing loss and associated hair cell degeneration by about a month,
providing enough time to inject
normal copies of the Clarin - 1
gene into the ear before the onset
of hearing loss to see if the treatment was effective.