Together, this translational program is developed within the National Cancer and Cognition Platform (CNO / Ligue Nationale contre le cancer), with the aim to collaborate in a structured way with French oncology groups, research teams as well as pharmaceutical industry, by
providing preclinical models and guidance on standard operating procedures for ancillary or future studies in identified population at risk.
Not exact matches
So similar are the two that researchers at the University of Georgia's Regenerative Bioscience Center have developed the first U.S. pig
model for stroke treatments, which will
provide essential
preclinical data and speed the drug discovery process.
These findings are promising for developing a
preclinical, large animal
model of Huntington's disease for assessing new therapeutics, which could ultimately
provide better treatment options, including altering the course of the disease.
«The
preclinical results in our animal
models are really exciting and have
provided the momentum for me to continue on this project, even after Novartis indicated that it no longer wished to maintain this collaboration.»
This
model offers unique capabilities for
preclinical assessment of thrombosis risk in a patient - specific manner, including efficacy testing of anti-thrombotic agents, elucidation of mechanism of action, and, potentially, biomarker identification, all
providing a much - needed platform for drug discovery and development.
«Nutrient scavenging by autophagy is a process that tumors hijack to meet their energetic requirements and to
provide the necessary cellular building blocks for growth in a stressed tumor micro-environment» said White, «
Preclinical models have demonstrated a critical role for autophagy in multiple cancer types.»
«Not only does this research
provide compelling evidence for further investigation of immunotherapy for treating stomach cancer, it also
provides the first
model for
preclinical testing of these treatments.»
Biomedcode is a Contract Research Organisation (CRO)
providing full
preclinical drug evaluation services to the pharmaceutical industry using a unique collection of mouse
models of human inflammatory diseases.
The goal of this Center of Excellence is to better define thrombus development in patients with cancer, test the efficacy of novel therapies, develop new
preclinical models, and create and expand biorepositories to
provide a valuable resource to researchers across Cleveland Clinic.
Overall, SR - Tiget represents a multi-disciplinary research environment, which
provides a unique blend of scientific expertise in the development of innovative gene and cell therapy strategies, access to relevant
preclinical models to evaluate their efficacy and safety, as well as competence in conducting early phase clinical trials.
The Bancroft laboratory was funded by TBVAC2020 to
provide preclinical animal
models to evaluate new TB vaccine candidates.
His research group actively collaborates with several pharmaceutical companies to
provide valuable
preclinical data in animal
models for their targeted drugs.