Not exact matches
«There are a lot of naturally occurring dog
diseases — especially
psychiatric diseases — that are very similar to human
diseases,» Hyun Ji Noh, a geneticist at the Broad Institute and the
lead author on the study, told Business Insider.
Today, the paradigm has widened into a much bigger idea that expands our understanding of
psychiatric disease: A whole host of infections and other unknown triggers
lead to the production of antibodies and immune cells that can cross into the brain.
«The practice of the Wim Hof Method may
lead to tonic changes in autonomous brain mechanisms, a speculation that has implications for managing medical conditions ranging from
diseases of the immune system to more intriguingly
psychiatric conditions such as mood and anxiety disorders,» said Diwadkar, professor of psychiatry and behavioral neurosciences.
One of the biggest surprises was that half of the 10
leading causes of disability were from
psychiatric conditions: depression, alcoholism, bipolar
disease, schizophrenia and obsessive - compulsive disorder.
The findings provide insight into the biological pathways that may predispose an individual to
disease and could ultimately
lead to the development of new therapeutic avenues to treat the five major
psychiatric illnesses.
New research
led by UC San Francisco scientists has revealed that mutations in a gene linked with brain development may dispose people to multiple forms of
psychiatric disease by changing the way brain cells communicate.
But when the enzymes are over-activated, the brain produces an excessive level of neurotoxic byproducts, causing neuronal dysfunctions that
lead to
psychiatric disorders and neurodegenerative
diseases.
In this paper, Fox
led a team that first conducted a large - scale literature search to identify all neurological and
psychiatric diseases where improvement had been seen with both invasive and noninvasive brain stimulation.
Despite the noble efforts of clinicians and researchers, our limited insight into the roots of
psychiatric disease hinders the search for cures and contributes to the stigmatization of this enormous problem, the
leading cause worldwide of years lost to death or disability.
Drawing upon genetic discoveries, Broad scientists are uncovering the biology that
leads to
disease, including cancer,
psychiatric disease, and immunological
disease, in order to identify potential new drug targets and new treatment strategies.
«In the future, these may
lead to treatments for a variety of brain disorders, including
psychiatric and cognitive conditions as well as neurodegenerative
diseases.»
Huntington's
disease (HD) is a lethal autosomal dominant neurodegenerative
disease that
leads to deficits in motor control and cognitive /
psychiatric functions.
This work should
lead to a better understanding of not only neuropsychiatric
diseases associated with autoantibodies but also of more common neurological or
psychiatric diseases in which similar protein dysfunction are reported.
Increased understanding of the developing brain and how deviations from normal development can increase the risk of neurological and
psychiatric diseases has created a rich landscape of opportunity for collaborations between
leading academic medical centers and pharmaceutical and biotechnology companies dedicated to identifying new drugs and other interventions to help children.
The failed attempts to define a function for DRD4 in
psychiatric and neurological conditions
led some to observe that DRD4 was a «gene in search of a
disease.»
By reprogramming human skin cells and other cells from patients with neurologic and
psychiatric diseases into induced pluripotent stem cells (iPSCs) and induced neurons (iN), his work seeks to decipher the progression and mechanisms that
lead to brain cell dysfunction.
Deficiency of folate and vitamin B12 is known to cause impaired methylation in the central nervous system, which may
lead to neurological
disease and other
psychiatric disorders.
Toxic metal exposure can result in a wide array of common mental health disorders that can mimic many
psychiatric «
diseases» and thus
lead to psychoactive prescription drug use or other unnecessary treatments.