«Parents»
psychiatric disease linked to kids» risk of suicide attempt, violent offending.»
Not exact matches
Of the thousands of ancestral variants reintroduced into modern humans, only 41 have been
linked in genetic studies to
diseases, such as skin conditions and neurological and
psychiatric disorders, he said.
New research led by UC San Francisco scientists has revealed that mutations in a gene
linked with brain development may dispose people to multiple forms of
psychiatric disease by changing the way brain cells communicate.
«Gene
links risk of
psychiatric disease to reduced synapse numbers.»
However, it is known to reside in brain tissue, and has been
linked to several
psychiatric diseases, including schizophrenia, bipolar disorder and suicidal behavior.
The findings also suggest that identifying the brain circuits affected by mutated genes
linked to
psychiatric disease could help scientists develop more personalized treatments for patients in the future, Feng says.
On the negative side, the researchers found that many of the genes whose activity is unique to modern humans are
linked to
diseases like Alzheimer's
disease, autism and schizophrenia, suggesting that these recent changes in our brain may underlie some of the
psychiatric disorders that are so common in humans today.
Within the fields of microbiology and immunology, neurologic
diseases, neuropharmacology, behavioral, cognitive and developmental neuroscience, and
psychiatric disorders, the center's research programs are seeking ways to: develop vaccines for infectious and noninfectious
diseases; understand the basic neurobiology and genetics of social behavior and develop new treatment strategies for improving social functioning in social disorders such as autism; interpret brain activity through imaging; increase understanding of progressive illnesses such as Alzheimer's and Parkinson's
diseases; unlock the secrets of memory; treat drug addiction; determine how the interaction between genetics and society shape who we are; and advance knowledge about the evolutionary
links between biology and behavior.
It's no mystery, then, why so many people with autoimmune
disease experience comorbid
psychiatric illnesses such as anxiety and depression, which are inextricably
linked to brain inflammation.
Studies done in 2010 showed a
link to gluten sensitivity and
psychiatric brain disorders like schizophrenia, 3 acute mania, 4 and bipolar disorders 5 without celiac
disease (gluten allergy).
Endophenotypes are measurable components that are hypothesized to lay on the pathway
linking the distal genotype with (
psychiatric)
disease.