Sentences with phrase «psychiatric disease models»

Since then we have tried to generate various types of neurological or psychiatric disease models such as a transgenic marmoset model of Alzheimer's disease.

Differentiation from human pluripotent stem cells of cortical neurons of the superficial layers amenable to psychiatric disease modeling and high - throughput drug screening.

Not exact matches

This is demonstrated in the studies reviewed in the special issue, which use computational models to examine brain processes, such as learning, emotion, dopamine signaling and information processing, and how processes interact in deficits underlying psychiatric disease.

In an e-mail to Nature a few days later, Kogan said that zebrafish might be a useful model organism for psychiatric disease after all.

The model expands the research toolkit for investigations of social behaviors and psychiatric diseases like autism and schizophrenia.

The new finding is the latest evidence supporting a growing precision medicine model of psychiatric disease in which disruptions of certain genes during brain development contribute to a person's risk for multiple psychiatric disorders, with other genetic or epigenetic drivers, random developmental events, or environmental influences determining the specific disease an individual develops, said senior author Benjamin Cheyette, MD, PhD, an associate professor of psychiatry and a member of the UCSF Weill Institute for Neurosciences and the Kavli Institute for Fundamental Neuroscience at UCSF.

«These are strong evidence that cave fish could be a good model for human psychiatric disease.»

The researchers» strategy — generating disease - specific nerve cells, identifying a causative gene for developmental defects, validating the gene - specific defect in animal models, and then investigating interactions with other genes both in animal models and in humans — represents a promising new approach for understanding the mechanisms underlying some of the most intractable psychiatric illnesses.

My current pursuit is the combination of MR Imaging, theoretical modeling and transgenic technology to elucidate the neurophysiological basis of functional conenctivity and its derangements in neurological and psychiatric disease.

Scientists working in computational psychiatry at Brown are thinking about how they can use their work modeling the brain to address psychiatric disease, such as depression.

In Singapore, cancer is still seen as a terminal disease with little hope of recovery, and there is also a stigma against psychological counselling and psychiatric support, facilitated by the general stigma against mental illness amongt both patients and, paradoxically, healthcare professionals.67 Furthermore, a family - centred model of decision - making tends to be predominant in Asian populations, 68 and in Singapore this is further encouraged by public policy such as healthcare subsidies that are based on a calculation of the immediate family's total income, rather than individual income.69 Beliefs or expectations of the role that the family caregiver ought to play may thus exist and may influence the way individuals respond to the intervention.

Other studies have shown that the number of psychiatric disorders a person has is related to life outcomes in young adulthood, 5 and that co-occurring mental disorders, to a small extent, influenced the consequences of anxiety and depression.3, 4, 23 More general personal traits such as childhood temperament and intellectual abilities are other individual factors that may be of importance, 26, 29 but the effects of intellectual function and psychiatric disease seem independent of each other.25 Our results indicated an influence of family factors, as indicated by the attenuation of OR in model 3.