The role of autonomy and
pubertal status in understanding age differences in diabetes responsibility across adolescence
Not exact matches
Pearson correlations and t tests were conducted to explore variation
in brain volumes related to children's sex, age,
pubertal status, history of psychiatric disorders (yes / no), and children's history of psychotropic medication use (yes / no).
Pubertal status was unrelated to metabolic changes
in any antipsychotic medication group.
The use of classical methods for assessing
pubertal status may not be feasible
in some studies, especially
in male adolescents.
These effects were qualified by group ×
pubertal status interaction effects (P < 0.001, 30 voxels contiguity) indicating that, contrary to hypotheses, the relationship between
pubertal maturation and response to rejection
in the left amygdala and caudate / sgACC was stronger among healthy controls than MDD youth.
Depression was associated with more mature
pubertal status and early timing (both actual and perceived)
in girls, but with less mature
pubertal status and late timing (actual and perceived)
in boys.
The objective of this study was to test a comprehensive model of biologic (
pubertal status), family (communication and conflict), and psychological influences (behavioral autonomy) on diabetes management and glycemic control
in a sample of youth (N = 226) with type 1 diabetes recruited during late childhood / early adolescence (ages 9 — 11 years).
Further, it was examined whether
pubertal status would be a more sensitive moderator
in these models compared to age.
In boys who reported low
pubertal status, both NCS (β =.48, p =.001) and stressors (β =.27, p =.002) were significantly associated with depressive symptoms.
The two - way interaction age (or
pubertal status) by gender (included
in all models under test) was not significant; whereas it would be expected that girls report more depressive symptoms as level of maturation (age /
pubertal status) increases compared to boys.
Results showed that although the four - way interaction between NCS, stressors, gender, and age was significant while the four - way interaction with
pubertal status was marginally significant, the interpretation of these interactions was largely similar, i.e., NCS and depressive symptoms were significantly related only
in the presence of many stressors
in middle to late adolescent boys (or
in boys reporting a high
pubertal status).
However, the current results do not seem to rule out that
pubertal status may have additional value
in examining cognitive models
in youth.
NCS was more strongly related to depressive symptoms
in boys with high
pubertal status that reported many (mean +1 SD) stressors (β =.73, p =.16) compared to boys with high
pubertal status reporting few stressors (β =.21, p =.74).
Pubertal status has been linked to the increase
in depressive symptoms
in girls (Angold and Costello 2006).
Moderation by
pubertal status instead of age yielded slightly different results, that is,
in the model with stress - reactive rumination, the relationship between negative cognitive style and depressive symptoms was stronger
in adolescents who perceived their
pubertal status as high, whereas age did not moderate this relationship.
The four - way interaction between NCS, stressors,
pubertal status, and gender approached significance (β = −.10, p =.08), indicating that the interaction between NCS and stressors was only significant
in boys who perceived their
pubertal status as high (β =.42, p =.007).
Some support has been found for an association between hormonal concentrations and negative affect20 - 24; however, social factors, including negative life events and their interaction with
pubertal status (but not hormonal
status), account for more of the variance
in negative affect than biological factors alone.25 Early
pubertal timing and its social implications have also been postulated as an important risk factor
in girls.26 - 31 Two recent studies, however, report that
pubertal status has a greater influence
in predicting female depression than age32, 33 or the timing of puberty.32
The results for
pubertal status and age are strikingly similar, indicating that after controlling for the effect of all the other variables
in the regression model, the impact of life events on depression is significantly greater
in the
pubertal girls (sex ×
pubertal status [age] × life events interaction).
Under 2 separate regression models (1 for
pubertal status and 1 for age), each variable's partial sums of squares and associated probability were used to examine these effects
in the 2 sexes together (Table 1).
Age - independent effects of
pubertal status on behavioral constraint
in healthy adolescents.
Future studies of the sources and consequences of EV may also want to include
pubertal status, as
pubertal status has been related to both depressive and aggressive affect (Brooks - Gunn et al. 1994), and recent evidence shows that
pubertal status and emotional reactivity to experimentally induced stress interact
in the prediction of internalizing symptoms (Leen - Feldner et al. 2007).
Thus, we controlled for three level 1 variables (age,
pubertal status, and treatment delivery method), two level 2 variables (baseline social
status and baseline BMI), and the interaction between age and BMI
in cross-sectional multilevel models.