Sentences with phrase «pure populations of»

However, with few exceptions, the stem cell and regenerative medicine industry has remained inadequately capitalized to carry out large - scale clinical trials independently, and major pharmaceutical firms have tended to show more interest in the use of hiPSCs as a source of large, pure populations of specific somatic cells for use in drug compound screening and toxicology tests, than they have in therapeutic uses of stem cells and their derivatives.

This approach not only enables us to get highly pure populations of DA progenitor cells (> 90 %), but it also increases our final yield of transplantable cells > 40 times when compared to previous embryoid body protocols starting with the same number of cells.

Functional and phenotypic differences of pure populations of stem cell - derived astrocytes and neuronal precursor cells.

«The ability to generate pure populations of these cell types is very important for any kind of clinically important regenerative medicine,» said Loh, «as well as to develop a basic road map of human embryonic development.

Researchers at the Stanford University School of Medicine have mapped out the sets of biological and chemical signals necessary to quickly and efficiently direct human embryonic stem cells to become pure populations of any of 12 cell types, including bone, heart muscle and cartilage.

The ability to make pure populations of these cells within days rather than the weeks or months previously required is a key step toward clinically useful regenerative medicine — potentially allowing researchers to generate new beating heart cells to repair damage after a heart attack or to create cartilage or bone to reinvigorate creaky joints or heal from trauma.

Genetically pure populations of westslope cutthroat trout are known to occupy less than 10 percent of their historical range.

Deng and his colleagues next induced the stem cells to develop into separate pure populations of astroglial cells and neurons.

The findings, published Aug. 31 in the journal Science Advances, could also lead to a simple, scalable and inexpensive way to manufacture a pure population of bone - building cells.

Although some teams have managed to produce nearly pure colonies of certain kinds of neural cells from ES cells, no one has managed to concoct a recipe that will direct the cells to become, say, a pure population of dopamine - producing neurons that could replace those missing in Parkinson's disease.

There is a plan, however, to maintain a genetically pure population of Cuban crocodiles by breeding the species and then releasing them into the wild.

According to the authors, future studies should aim to improve the efficiency of the approach to generate a pure population of cells that closely mimic adult Leydig cells.

After this period of induction, keratinocytes derived from pluripotent stem cells were isolated and amplified to obtain a homogenous and pure population of keratinocytes presenting all the phenotypic characteristic of adult keratinocytes.

Having a pure population of cardiac muscle cells is essential for avoiding tumor formation after transplantation, but has been technically challenging.

The goal is to help researchers establish a pure population of subjects who truly have the disease, ultimately enabling the discovery of pathogenic pathways.

Sorting breast cancer cells using a new reporter construct allows the interrogation of a highly pure population of cancer stem cells and may allow for the discovery of new therapeutic targets

Because the antigen detected is produced only by the female worm, a pure population of male heartworms will also give a false negative.

There is prolific wildlife throughout the Island: visitors can expect to see some of the 325 species of birds including Australia's stork, the jabiru, several species of wallaby, possums, flying foxes, echidnas and eastern Australia's purest population of dingo.

The wildlife that visitors to Fraser Island can expect to see is some of the hundreds of species of birds including Australia's stork, the jabiru, possums, flying foxes, echidnas and eastern Australia's purest population of dingo.

Not exact matches

Economics Sometimes the price difference really is pure economics: Canada is a sprawling country with a small population, which means higher costs for shipping, storage, distribution and economies of scale.

For the United States, with its population of 320 million at the time of that study, the pure economic payoff was thus only $ 400 per person, while per capita GDP was close to $ 50,000.

Jeremy before the Gospel was preached in New Zealand my people the maori people already had many gods and lived under there own type of spiritual law.They had rituals to keep themselves holy or pure but was by works.They also believed that there was one supreme God who was above all other Gods and his name was eo.So when the Missionaries came they understood the message of a supreme God and the way to know him was through his son over 60 % of maori people accepted the Gospel.It was bigger revival than the welsh revival in terms of percentage of population the welsh revival was only 10 % of the population of wales and that was considered a large revival in its day the new zealand revival was in the years 1820 - 1840.

All those within Torah Musa, Zabor Dawoud, Angeel Issa out of which brewed out of it the soul thing of pure faith that God was not not begotten, God is Single and not Plural, God has no Mistress, God has No Begotten Son, God may Chose Any as Sons from his creations with out need to beget sons through the means he created for mankind to increase population... All Prophets and Messengers spoke the Words of God as he put his words to their mouths... they were the words of God... Now please read with me the verses even if for general informations only;

Depending on which poll and datapoint and question formulation you take (ex1, ex2, ex3), pure atheists (as opposed to agnostics or no - declared - religion people) in USA make up between 1 % and 3 % of population, and even far wider «no declared belief» category i only ~ 10 %.

The research showed that, compared to pure snow and ice, the reflectivity of the glacier (known as the «albedo») can be reduced by up to 80 % in places where coloured microbial populations are extremely dense, leading to the darkening of the glacier surface.

The result: tiny green spheres about half a millimeter across, «a population of pure, early lung cells,» says Hawkins.

They developed a streamlined and fast, though inexpensive, method that allows direct access to a pure and vital population of zebrafish OPCs in less than 2 hours.

«We can falsify this notion that anyone is pure,» says population geneticist Lynn Jorde of the University of Utah in Salt Lake City.

Our results suggest that in addition to «pure» species and populations, hybrids between protected animals and non-protected ones may deserve protection,» said Robert Wayne, a biologist at University of California Los Angeles and senior author of the study.

James Hansen of the Goddard Institute for Space Studies argues that China and India will make this decision out of pure self - interest, since rising sea levels could place large portions of their coastal populations at risk.

«Those approaches take a long time, it is difficult to isolate a pure population, and the NPC - like cells are still transient,» says Zhongwei Li, a research associate in the Izpisua Belmonte lab and co-first author of the new paper.

In the Calnali River in Mexico, two pure species of swordtail fish live side by side with a third population that's a mix of the original two.

«The PURE study is observational in design and does not test directly whether reducing sodium intake in a population reduces cardiovascular disease outcomes compared to a comparable population, selected at random, that consumes moderate amounts of sodium.»

Developing therapeutic cell populations from human ES cells will be far more demanding: cells will have to be stable, predictable, pure, have proven functionality, be nontumor - forming, and be «scalable» — capable of growing in very large numbers.

The ability to isolate pure CSC populations using cellular markers has led to advances in our understanding of the heterogeneity and plasticity of the CSC phenotype.

This led researchers from the group of Joseph S. Anderson (University of California Davis, USA) to formulate a new strategy; the use of a combined anti-HIV and selection vector [5, 6] to enrich for modified HSPCs, to provide a pure and effective cell population for therapeutic purposes.

Demography and evolution of pure hybridogenetic frog (Rana esculenta) populations.

«We found that while hybridisation has not compromised the genetic distinctiveness of wolf populations, a large number of wild wolves in Eurasia carry a small proportion of gene variants derived from dogs, leading to the ambiguity of how we define genetically «pure wolves».

This suggests that the definition of genetically «pure» wolves can be ambiguous and identifying admixed individuals can be difficult, implying that management strategies based on removal of suspected hybrids from wolf populations may be inefficient.

The introduction of the Texas panthers was controversial, Pimm says, in part because researchers thought it would result in the loss of the «pure» Florida population.

So, like I kind of alluded to earlier, we've got a lot of athletes, a lot of exercise enthusiasts that listen into the show, and simply as a pure result of movement, they tend to eat more calories than the general population.

The original host's son, Peter Gaulke (Steven Zahn), has taken up his father's mantle, but Peter has no discernible knowledge of animals, and his onscreen narration is full of gross misinformation («Bears derive their name from a football team in Chicago»), grosser jokes and pure nonsense («Monkeys make up more than 80 percent of the world's monkey population»).

So far there has been a pitifully small addition each year to the High Needs Block pot to recognise changing population, but it's been allocated on pure pupil numbers, without any recognition of levels of SEND which vary between authorities.

While in many shelters Pit Bulls are over represented in comparison to other pure breeds this is not due to an over population issue but more due to bad internal adoption policies within many humane organizations and of a lack of understanding about the breed resulting in an unnatural deflatation in demand.

Pure breeds have been, for the most part, artificially created from random - bred populations by human selective breeding with the purpose of enhancing desired physical, behavioral, or temperamental characteristics.

They don; t want pure bred animals available, Hey, not all of the population gets good warm fuzzy feelings from having a huge black, unruly adult dog that is impossible to handle or train?

«Pure bred» cats are uncommon and comprise approximately 3 - 5 % of the cat population on this continent but, there are over 40 breeds recognized among all of the feline registry organizations in North America.

In our study, we employed a more stringent study design — restricting the study population to AKC registered, pure - bred dogs of one breed, carefully quantitating the lifetime duration of ovarian exposure — in order to lessen the likelihood of such bias.

Worse yet, the health of the general pet population is adversely affected when these geneticly defective pure bred pets are left unaltered and allowed to breed with healthy pets.

There has been only pure - blood breeding within the population of the new breed since.